Results 61 to 70 of about 1,763,020 (300)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Impact of the COVID‐19 lockdown on patients and families with Dravet syndrome

Epilepsia Open, 2021
We explored the impact of coronavirus virus 2019 (COVID‐19) pandemic on patients with Dravet syndrome (DS) and their family. With European patient advocacy groups (PAGs), we developed an online survey in 10 languages to question health status, behavior ...
Isabella Brambilla, José Ángel Aibar, Anne Sophie Hallet, Irena Bibic, Elena Cardenal‐Muñoz, Igor Prpic, Francesca Darra, Nicola Specchio, Rima Nabbout   +8 more
doaj   +1 more source

Local Density of the Bose Glass Phase [PDF]

, 2018
We study the Bose-Hubbard model in the presence of on-site disorder in the canonical ensemble and conclude that the local density of the Bose glass phase behaves differently at incommensurate filling than it does at commensurate one.
Hettiarachchilage, K., Jarrell, M., Moore, C., Moreno, J., Rousseau, V. G., Tam, K. -M.   +5 more
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Sociological and Human Developmental Explanations of Crime: Conflict or Consensus [PDF]

, 1985
This paper examines multidisciplinary correlates of delinquency in an attempt to integrate sociological and environmental theories of crime with human developmental and biological explanations of crime.
Andrew June, Austin, Bogen, Carter-Saltzrnan, Center for Studies in Criminology, Climent, Cowie John, Darlington, Datesman, Davie Ronald, Denhoff Eric, Denno Deborah, Dimond, Eagle David B., Elliott, Elliott Delbert, Frisch, Gabrielli, Gabrielli, Garmezy Norman, Gevins, Goldberger, Hirschi Travis, Hirschi Travis, Jencks Christopher, Jensen, Joreskog, Joreskog, Katz, Kirkegaard-Sorenson, Konopka Gisela, Kornhauser Ruth, McGlone Jeanette, McMahon, Mednick, Nachshon Israel, Nichols, Niswander, Offord, Paternoster Raymond, Prahl-Andersen, Reinisch, Reitan, Rie, Schur, Schweinhart, Shah Saleem, Shapiro Theodore, Simpson, Slone Dennis, Sutherland Edwin, Thompson, US. Department of Health, Education, and Welfare, Vera Institute of Justice, Virkunnen Matti, Wender, West Donald, Wilson, Wittig, Wolfgang, Wolfgang, Zellermayer Joseph, Zinkus   +62 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Behavioral and developmental disorders among conduct disorder [PDF]

Psychiatry and Clinical Neurosciences, 2002
AbstractThe purpose of the present study was to clarify the percentage of children with conduct disorder (CD) who also have behavioral and developmental disorders. A survey of comorbidity observed in children with CD, was carried out on 33 subjects from a disciplinary facility for children.
Yuzuru, Harada, Yuri, Satoh, Ayako, Sakuma, Junko, Imai, Tunemi, Tamaru, Tohru, Takahashi, Naoji, Amano   +6 more
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Reconceptualizing attrition in Parent–Child Interaction Therapy: “dropouts” demonstrate impressive improvements

Psychology Research and Behavior Management, 2019
Corey C Lieneman,1 Lauren B Quetsch1,2, Laurie L Theodorou,3 Kathleen A Newton,3 Cheryl B McNeil11Department of Psychology, West Virginia University, Morgantown, WV, USA; 2Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock,
Lieneman CC, Quetsch LB, Theodorou LL, Newton KA, McNeil CB   +4 more
doaj