Results 91 to 100 of about 1,703,732 (307)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Treatment Outcomes for At-Risk Young Children With Behavior Problems: Toward a New Definition of Success [PDF]

open access: yes, 2014
This study examined the outcomes of Early Pathways (EP), an in-home parent–child therapy program with 447 at-risk children younger than 5 years of age who were referred for severe behavior and emotional problems, such as aggression, oppositional behavior,
Fox, Robert A.   +2 more
core   +1 more source

Criterion validity of the Multidimensional Scale of Irrational Beliefs (MSIB) with respect to anxiety, depression, and life satisfaction [PDF]

open access: yes, 2008
Using a sample of 200 participants, this study seeks to establish criterion validity of the Multidimensional Scale of Irrational Beliefs (MSIB), a newly developed, purely cognitive measure of irrational beliefs.
Bekk, Magdalena   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Behavior Modification

open access: yes, 1999
Excerpt: Behavior modification is learning with a particular intent, namely clinical treatment and change (Ullmann & Krasner, 1965, p. 1). Initially behavior modification referred largely to operant techniques and behavior therapy to respondent ...
Bufford, Rodger K.
core  

ANCOVA Study of Psychotherapy Treatment of Internet Pornography Addiction in Heterosexual Men [PDF]

open access: yes, 2015
Internet pornography has grown to become a problem that exists within the United States and across the globe. For those who suffer from this problematic behavior experience individual and familial problems as well as cause damage to the psyche ...
Twine, Saudia L
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Home-Based Parent-Child Therapy in Low-Income African American, Caucasian, and Latino Families: A Comparative Examination of Treatment Outcomes [PDF]

open access: yes, 2014
This study examined parent and child treatment outcomes for a home-based Parent-Child Therapy (PCT) program for 66 children from families living in poverty.
Gresl, Brittany L.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Interpersonal Behavior in Couple Therapy: Concurrent and Prospective Associations with Depressive Symptoms and Relationship Distress [PDF]

open access: yes, 2018
Objective: This study investigated associations between couples’ interpersonal behavior, depressive symptoms, and relationship distress over the course of couple psychotherapy.
Knobloch-Fedders, Lynne M.   +1 more
core   +1 more source

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