Results 81 to 90 of about 1,703,732 (307)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Latino Acculturative Stress Implications, Psychotherapeutic Processes, and Group Therapy [PDF]

open access: yes, 2012
The Latino population is the fastest growing ethnic minority group in the United States. Yet, Latinos do not receive adequate mental health treatment due to the lack of cultural sensitivity regarding the necessity of bilingual and bicultural staff and ...
Doucette, David W, Russell, Micah
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Development of the Multidimensional Scale of Irrational Beliefs (MSIB) [PDF]

open access: yes, 2008
The Multidimensional Scale of Irrational Beliefs (MSIB) is a brief and theoretically founded measure of irrational thinking as conceptualized by Albert Ellis in his most recent works on Rational Emotive Behavior Therapy (e.g., Ellis, 2003).
Bekk, Magdalena   +4 more
core   +1 more source

Behavioral alarm treatment for nocturnal enuresis

open access: yesInternational Brazilian Journal of Urology, 2010
PURPOSES: To investigate the efficacy of alarm treatment in a sample of Brazilian children and adolescents with nocturnal enuresis and relate treatment success to age and type of clinical support.
Rodrigo F. Pereira   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Psychoanalytic and cognitive-behavior therapy of chronic depression : study protocol for a randomized controlled trial [PDF]

open access: yes, 2012
Background: Despite limited effectiveness of short-term psychotherapy for chronic depression, there is a lack of trials of long-term psychotherapy. Our study is the first to determine the effectiveness of controlled long-term psychodynamic and cognitive ...
Bahrke, Ulrich   +8 more
core   +1 more source

The Impact of Disease on Behavior: Altering Behavior in the Course of Disease in Aging Cats

open access: yesPets
Associations between age-related diseases and behavioral alterations have been highlighted in previous studies. This study investigates the prevalence of diseases and behavioral changes in non-diseased and diseased senior cats before and after diagnosis,
Joana Eisinger, Franziska Kuhne
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

ISLAMIC PSYCHOLOGY IN TREATING VICTIMS OF CHILD SEXUAL ABUSE (Family Therapy and Story Telling Therapy) IN TREATING VICTIMS OF CHILD SEXUAL ABUSE [PDF]

open access: yes, 2016
The purpose of this study was to describe the changes experienced by the subjects after family therapy and storytelling therapy. This research used descriptive qualitative study with Curative Therapy methods and the Observational Analysis.
Desiningrum, Dinie Ratri
core  

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