Results 121 to 130 of about 1,703,732 (307)

Personality traits and physical activity in patients with gambling disorder attending a rehabilitation center. An observational study

Frontiers in Psychology
ObjectiveProblem gambling is associated with various negative health behaviors, such as physical inactivity. However, physical activity may also be used as a coping mechanism to manage stress and anxiety.
Inmaculada Fierro, Raúl Fernández-Prieto, Alicia Fernández-Parra, Miriam Herrero-Martín, Azael J. Herrero, Azael J. Herrero   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Efektivitas Cognitive Behavior Therapy Dengan Media Bermain Untuk Menurunkan Reaksi Kecemasan Di Sekolah Pada Anak Dengan Taraf Intelektual Borderline [PDF]

, 2013
Penelitian ini bertujuan untuk mengetahui apakah cognitive behavior therapy dengan media bermain dapat menurunkan reaksi kecemasan pada anak dengan taraf intelektual borderline.
Arum S, Angelina Dyah, Roswita, M. Y. (M), Widyorini, E. (Endang)   +2 more
core   +1 more source

DRA dengan Token Ekonomi untuk Menurunkan Perilaku Makan yang Menyimpang: Sebuah Studi Kasus pada Anak

Gadjah Mada Journal of Professional Psychology
Children of homeless people often experience various issues, one of which is eating behavior problems. Eating food from trash cans is a common eating behavior problem encountered. Therefore, an intervention is needed to reduce this issue. This case study
Smita Dinakaramani
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The Effectiveness of Behavior Modification : Food Diet and Drug Therapy Toward Attention Deficit and Hyperactivity Disorder Children's Behavior [PDF]

, 2008
Most parents of Attention Deficit and Hyperactivity Disorder (ADHD) children in Indonesia refused to use drug continuously because they were worry about it side effect.
Nanik, Nanik
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Brief intermittent intense exercise as interoceptive exposure for panic disorder: a randomized controlled clinical trial

Frontiers in Psychiatry
BackgroundInteroceptive exposure (IE) to feared bodily sensations is a core component of cognitive–behavioral therapy for panic disorder (PD), but standard office-based IE can be perceived as aversive and tedious, potentially limiting engagement ...
Ricardo William Muotri, Alan Campos Luciano, Alia Garrudo Guirado, Francisco Lotufo Neto, Márcio Bernik   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source