Results 131 to 140 of about 1,703,732 (307)

Case Report of Writers Cramp Syndrome Along with Myoclonic Epilepsy and Compulsion

پزشکی بالینی ابن سینا, 2009
Introduction: The writer's cramp syndrome is a kind of local dystonia which appears in the hands due to uncontrollable muscular spasms, making a hard and tiring job of writing for patients.
Alireza Moghaddas, Mitra Nasseri
doaj  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Development of a Barriers Scale to Predict Early Treatment Success for Young Children in Poverty with Behavior Problems [PDF]

, 2016
Research has demonstrated that participation in parent and child therapy (PCT) programs significantly reduces problematic behaviors while increasing positive behaviors in the child.
Besasie, Lauryn A., Fox, Robert A., Gresl, Brittany Lynn   +2 more
core   +1 more source

From surgical treatment to psychiatric progress in refractory obsessive–compulsive disorder: A case report

PCN Reports
Background Obsessive–compulsive disorder (OCD) can cause physical complications, and psychiatric treatment sometimes improves these complications. However, it remains unclear whether managing a physical complication can contribute to the improvement of ...
Shotaro Fujiwara, Yasushi Okamura, Hitomi Wake, Hideaki Tanami, Takuto Ishida, Masafumi Mizuno   +5 more
doaj   +1 more source

Effects of a mobile health intervention on health-related outcomes in Japanese office workers: a pilot study

International Journal of Occupational Medicine and Environmental Health
Objectives The purpose of the current study was to explore the effects of a mobile health (mHealth) intervention based on the Persuasive System Design (PSD) model on health-related outcomes among office workers.
Takumi Meguro, Fuminori Takayama, Hampus Hammarlund, Masaru Honjo   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Efektivitas Cognitive Behavior Therapy Untuk Menurunkan Kecemasan Berbicara Di Depan Umum Pada Mahasiwa [PDF]

, 2017
Kompetensi mahasiswa dalam berbicara di depan umum dalam lingkup akademis telah menjadi tuntutan yang sewajarnya guna menyiapkan mahasiswa memiliki daya saing yang tinggi dan sebagai bekal kehidupan bermasyarakat.
Fitri, D. (Dian)
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Aversion Therapy

, 1999
Excerpt: Aversion therapy uses a number of techniques and stimuli to weaken or eliminate undesirable responses such as deviant sexual behavior and substance abuse.
Bufford, Rodger K.
core