Results 151 to 160 of about 18,395,743 (310)
Comparison of responsibilities of occupational therapy practitioners in school-based practice
, 2011 "Originally Published February 2010--Revised March 2011"--P. [1]; "Published February 2010"--P. [2]
core
Case Report of Writers Cramp Syndrome Along with Myoclonic Epilepsy and Compulsion
پزشکی بالینی ابن سینا, 2009 Introduction: The writer's cramp syndrome is a kind of local dystonia which appears in the hands due to uncontrollable muscular spasms, making a hard and tiring job of writing for patients.
Alireza Moghaddas, Mitra Nasseri
doaj
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Text-book of Osteopathy : from the Standpoint of Mechano-Therapy
, 1910 This treatise on Osteopathy presents a few of the essentials of one branch of Mechano-Therapy, the eclectic system of Drugless Healing. For we beg to remind the reader that the application of the principles of Osteopathy alone is just as insufficient ...
American College of Mechano-Therapy
core +1 more source
PCN ReportsBackground Obsessive–compulsive disorder (OCD) can cause physical complications, and psychiatric treatment sometimes improves these complications. However, it remains unclear whether managing a physical complication can contribute to the improvement of ...
Shotaro Fujiwara +5 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source