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Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara+14 more
wiley +1 more source
Predicting Treatment Success in Child and Parent Therapy Among Families in Poverty [PDF]
Behavior problems are prevalent in young children and those living in poverty are at increased risk for stable, high-intensity behavioral problems. Research has demonstrated that participation in child and parent therapy (CPT) programs significantly ...
Fox, Robert A.+2 more
core +1 more source
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang+3 more
wiley +1 more source
TERAPI BERMAIN UNTUK MENINGKATKAN KONSENTRASI ANAK DENGAN GANGGUAN ADHD [PDF]
Concentration of attention and hyperactivity disorders commonly called ADHD or lately a lot found in children - children who have traits that are very short attention span than other kids his age, usually accompanied by hyperactivity and impulsive ...
Wahyuni, Lina Indah
core
Comprehensive Joint Modeling of First-Line Therapeutics in Non-Small Cell Lung Cancer [PDF]
First-line antiproliferatives for non-small cell lung cancer (NSCLC) have a relatively high failure rate due to high intrinsic resistance rates and acquired resistance rates to therapy. 57% patients are diagnosed in late-stage disease due to the tendency of early-stage NSCLC to be asymptomatic. For patients first diagnosed with metastatic disease the 5-
arxiv
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou+11 more
wiley +1 more source
Combination Therapy for Chronic Hepatitis B Using Capsid Recycling Inhibitor [PDF]
In this paper, we investigate the dynamics of hepatitis B virus infection taking into account the implementation of combination therapy through mathematical modeling. This model is established considering the interplay between uninfected cells, infected cells, capsids, and viruses. Three drugs are considered for specific roles (i) pegylated interferon (
arxiv