Results 211 to 220 of about 1,703,732 (307)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Rational emotive behavior therapy for preventing smoking initiation among school children: Addressing peer influence and social susceptibility. [PDF]

J Taibah Univ Med Sci
Simarmata SW, Batubara A, Sagita DD, Violina EI, Syaikhu A, Simangunsong J.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Effects of group cognitive behavior therapy on cognitive flexibility in college students with high obsessive-compulsive symptoms. [PDF]

Front Psychol
Ji S, Liu Y, Chen L, Zhang W, He K.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Observational Comparison of Outcomes of Sandplay Therapy (SPT-SAFE) Versus Dialectical Behavior Therapy (DBT-BI) for Elementary School Students with NSSI and Suicidal Ideation: A Retrospective School-Based Study. [PDF]

Behav Sci (Basel)
Kwak H, Ahn U.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Guided Internet-Based Cognitive Behavior Therapy for Women With Bulimia Nervosa: A Randomized Clinical Trial.

JAMA Netw Open
Hamatani S, Matsumoto K, Andersson G, Sato Y, Fukudo S, Sudo Y, Hirano Y, Ino K, Ishibashi T, Tomioka Y, Umehara H, Numata S, Nakamura M, Otani R, Sakuta R, Sekiguchi A, Kosaka H, Mizuno Y, HOPE Project Consortium, Kamashita R, Yoshida T, Matsuura K, Tomari S, Funaba M, Sasaki N, Sako H, Shimada S, Inoue T.   +27 more
europepmc   +1 more source