From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Psychological Intervention for Button Phobic [PDF]
, 2011 Behavior therapy approach is used in psychological intervention of button phobic, including systematic desensitization, relaxation, cognitive-behavioral therapy, modelling and skill training therapy.
Nanik, Nanik
core
Efektivitas Rational Emotive Behaviour Therapy Berdasarkan Profile Multimodal Therapy Pada Klien Skizofrenia Dengan Masalah Keperawatan Perilaku Kekerasan Dan Halusinasi Di Rumah Sakit Jiwa [PDF]
, 2015 This study aims to determine the effectiveness of rational emotive behavior therapy (REBT) profile of multimodal therapy based on the client\u27s ability and changes in symptoms violent behavior and hallucinations in Psychiatric Hospital.
Hastuti, R. Y. (Retno) +2 more
core +2 more sources
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Interpersonal Behavior in Couple Therapy: Concurrent and Prospective Associations with Depressive Symptoms and Relationship Distress [PDF]
, 2018 Objective: This study investigated associations between couples’ interpersonal behavior, depressive symptoms, and relationship distress over the course of couple psychotherapy.
Knobloch-Fedders, Lynne M. +1 more
core +1 more source
Bullying girls - Changes after brief strategic family therapy: A randomized, prospective, controlled trial with one-year follow-up [PDF]
, 2005 Background: Many girls bully others. They are conspicuous because of their risk-taking behavior, increased anger, problematic interpersonal relationships and poor quality of life.
Burdsal C +27 more
core +1 more source
Chronic Diseases Journal, 2020 BACKGROUND: A transtheoretical model (TTM) can be considered as a cognitive and motivational view, a component which plays a significant role in addiction.
Mehdi Panahi, Paria Sadeghi
doaj +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Penerapan Cognitive Behavior Therapy (CBT) Terhadap Pengurangan Durasi Bermain Games Pada Individu Yang Mengalami Games Addiction [PDF]
, 2013 Studi ini menggunakan pendekatan kualitatif dengan metode studi kasus, yang bertujuan untuk memperoleh gambaran menyeluruh dari penerapan Cognitive Behavior Therapy (CBT) dalam membantu individu mengurangi durasi bermain games pada individu yang ...
Siregar, E. Y. (Elna)
core +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source