Results 81 to 90 of about 11,021,950 (406)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Psychological Intervention for Button Phobic [PDF]

open access: yes, 2011
Behavior therapy approach is used in psychological intervention of button phobic, including systematic desensitization, relaxation, cognitive-behavioral therapy, modelling and skill training therapy.
Nanik, Nanik
core  

Initiation of HIV therapy [PDF]

open access: yes, 2010
In this paper, we numerically show that the dynamics of the HIV system is sensitive to both the initial condition and the system parameters. These phenomena imply that the system is chaotic and exhibits a bifurcation behavior.
BINGO WING-KUEN LING   +2 more
core   +1 more source

"Honey, Tell Me What's Wrong", Global Explanation of Textual Discriminative Models through Cooperative Generation [PDF]

open access: yesarXiv, 2023
The ubiquity of complex machine learning has raised the importance of model-agnostic explanation algorithms. These methods create artificial instances by slightly perturbing real instances, capturing shifts in model decisions. However, such methods rely on initial data and only provide explanations of the decision for these.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Interpersonal Behavior in Couple Therapy: Concurrent and Prospective Associations with Depressive Symptoms and Relationship Distress [PDF]

open access: yes, 2018
Objective: This study investigated associations between couples’ interpersonal behavior, depressive symptoms, and relationship distress over the course of couple psychotherapy.
Knobloch-Fedders, Lynne M.   +1 more
core   +1 more source

Software for web-based tic suppression training [version 2; referees: 3 approved] [PDF]

open access: yes, 2018
Exposure and response prevention (ERP) is a first-line behavior therapy for obsessive-compulsive disorder and Tourette syndrome (TS). However, ERP for tic disorders requires intentional tic suppression, which for some patients is difficult even for brief
Black, Jonathan K, Black, Kevin J
core   +2 more sources

Usability of a Robot's Realistic Facial Expressions and Peripherals in Autistic Children's Therapy [PDF]

open access: yesarXiv, 2020
Robot-assisted therapy is an emerging form of therapy for autistic children, although designing effective robot behaviors is a challenge for effective implementation of such therapy. A series of usability tests assessed trends in the effectiveness of modelling a robot's facial expressions on realistic facial expressions and of adding peripherals ...
arxiv  

Personalized Machine Learning for Robot Perception of Affect and Engagement in Autism Therapy [PDF]

open access: yes, 2018
Robots have great potential to facilitate future therapies for children on the autism spectrum. However, existing robots lack the ability to automatically perceive and respond to human affect, which is necessary for establishing and maintaining engaging interactions.
arxiv   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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