Results 21 to 30 of about 593,000 (263)

The phytochemical and pharmacological profile of taraxasterol

Frontiers in Pharmacology, 2022
Taraxasterol is one of the bioactive triterpenoids found in dandelion, a member of the family Asteraceae. In the animal or cellular models of several ailments, including liver damage, gastritis, colitis, arthritis, pneumonia, tumors, and immune system ...
Fengjuan Jiao, Fengjuan Jiao, Zengyue Tan, Zengyue Tan, Zhonghua Yu, Zhonghua Yu, Bojie Zhou, Bojie Zhou, Lingyan Meng, Lingyan Meng, Xinyue Shi, Xinyue Shi   +11 more
doaj   +1 more source

SUMOylation of Warts kinase promotes neural stem cell reactivation

Nature Communications
A delicate balance between neural stem cell (NSC) quiescence and proliferation is important for adult neurogenesis and homeostasis. Small ubiquitin-related modifier (SUMO)-dependent post-translational modifications cause rapid and reversible changes in ...
Yang Gao, Ye Sing Tan, Jiaen Lin, Liang Yuh Chew, Htet Yamin Aung, Brinda Palliyana, Mahekta R. Gujar, Kun-Yang Lin, Shu Kondo, Hongyan Wang   +9 more
doaj   +1 more source

Human pluripotent stem cell (hPSC)-derived microglia for the study of brain disorders. A comprehensive review of existing protocols

IBRO Neuroscience Reports
Microglia, resident immune cells of the brain that originate from the yolk sac, play a critical role in maintaining brain homeostasis by monitoring and phagocytosing pathogens and cellular debris in the central nervous system (CNS).
Fionicca Teo, Catherine Yen Li Kok, Mao-Jia Tan, H. Shawn Je   +3 more
doaj   +1 more source

Problem Gambling among Adolescent Girls in Croatia—The Role of Different Psychosocial Predictors

Frontiers in Psychology, 2017
Although, compared to boys, adolescent girls gamble less often and less problematically, prevalence studies still show significant numbers of at risk/problem gamblers among girls.
Aleksandra Huic, Dora Dodig Hundric, Valentina Kranzelic, Neven Ricijas   +3 more
doaj   +1 more source

Social Deficits or Interactional Differences? Interrogating Perspectives on Social Functioning in Autism

Frontiers in Psychiatry, 2022
Social dysfunction is a key characteristic of autism. Determining and treating autism-related social deficits have been challenging. The medical model views interpersonal difficulties in autism as a localized set of deficits to be managed, whereas the ...
Xiangting Bernice Lin, Xiangting Bernice Lin, Choon Guan Lim, Choon Guan Lim, Choon Guan Lim, Tih-Shih Lee, Tih-Shih Lee   +6 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Physiological paradigm for assessing reward prediction and extinction using cortical direct current potential responses in rats

Scientific Reports
Anticipating positive outcomes is a core cognitive function in the process of reward prediction. However, no neurophysiological method objectively assesses reward prediction in basic medical research.
Yoshiki Matsuda, Nobuyuki Ozawa, Takiko Shinozaki, Yoshitaka Tatebayashi, Makoto Honda, Toshikazu Shinba   +5 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Determinants of experience & satisfaction in telehealth psychiatry during the COVID-19 pandemic for patients & providers

Frontiers in Psychiatry, 2023
IntroductionThe objective of this study was to characterize the experiences and overall satisfaction of patients and providers with the March 2020 transition to telehealth in a psychiatric setting (telepsychiatry).
Michael Morreale, Ilana Cohen, Michael Van Wert, Alexis Beccera, Leslie Miller, William Narrow, Barbara Schweizer, Jason Straub, Peter Zandi, Anne Ruble   +9 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source