Results 101 to 110 of about 2,169,855 (259)
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
COVID-19 vaccination and the behavioral immune system: The newcomer and the old friend get along in preventing infection. [PDF]
Troisi A +4 more
europepmc +1 more source
The Role of the Immune System in Behavioral Strategies of Reproduction
Since both reproduction and immunocompetence are costly, the negative reciprocal relationships between these functions were found in many species. Due to reproductive immunosuppression, some fraction of seasonally breeding populations of small mammals reproduces in the first breeding season, while others reproduce in the next one. Elevation of breeding
Moshkin, Mikhail P. +2 more
openaire +2 more sources
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Background and Objective: Several studies revealed that disgust as an emotional response underlies the contamination fears in Contamination Obsessive Compulsive Disorder (OCD).
Mona Moradi Motlagh +4 more
doaj
Effects of Spicy Food on Sense of Fairness: Mediating Effects of Aggression and Pathogen Avoidance
Spicy food consumption is prevalent worldwide, yet its psychological and behavioral impacts remain underexplored compared to basic tastes like sweet, sour, salty, bitter, and umami.
Weixi Wan, Yanping Shangguan, Qi Wu
doaj +1 more source
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
The behavioral immune system and use of transportation services during the COVID-19 pandemic. [PDF]
Sevi B, Shook NJ.
europepmc +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

