Results 81 to 90 of about 2,169,855 (259)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Implicit Attitudes About Agricultural and Aquatic Products From Fukushima Depend on Where Consumers Reside

Frontiers in Psychology, 2019
Japanese consumers are still hesitant to purchase products from Fukushima, although 7 years have passed since the Fukushima nuclear disaster, and these products are officially considered safe.
Otgonchimeg Tsegmed, Daiki Taoka, Jiang Qi, Atsunori Ariga   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Reciprocal Interactions Between Gut Microbiota and Host Social Behavior

Frontiers in Integrative Neuroscience, 2018
Animals harbor an extensive, dynamic microbial ecosystem in their gut. Gut microbiota (GM) supposedly modulate various host functions including fecundity, metabolism, immunity, cognition and behavior. Starting by analyzing the concept of the holobiont as
Emmanuelle Münger, Augusto J. Montiel-Castro, Wolfgang Langhans, Gustavo Pacheco-López, Gustavo Pacheco-López   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Tolerating Injustice When Feeling in Control: Personal Control Enhances the Link Between Collectivism and Coercion in the Face of Disease Threats

Social Psychological Bulletin
Amid the COVID-19 pandemic, authorities worldwide imposed coercive regulations aimed at curbing the virus’s spread, often at the expense of individuals who were considered potential threats to public health.
Nan Zhu, Yang Li, Lei Chang
doaj   +1 more source

A novel Artificial Immune System for fault behavior detection

Expert Systems with Applications, 2011
AbstractThis paper presents an error detection methodology to enable fault detection inspired on recent immune theory. The fault detection problem is a challenging problem due to processes increasing complexity and agility necessary to avoid malfunction or accidents.
C. A. Laurentys, Reinaldo M. Palhares, Walmir M. Caminhas   +2 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Frontal alpha asymmetries and behavioral immune system: moderating role of behavioral inhibition system

Periodicum Biologorum
Background and purpose: Behavioral immune system is a cluster of psychological mechanisms enabling detection and avoidance of pathogens in one’s immediate environment. Its presumed activation has been implicated in myriads of psychological phenomena, stemming from pathogen related disgust to more complex behaviors, such as mate choice and xenophobic ...
Ivana Hromatko, Andreja Bubić
openaire   +1 more source