Results 51 to 60 of about 4,194,676 (300)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Psychological Co-Morbidities of Physical Illness: A Behavioral Medicine Perspective

open access: yes, 2011
Summary: Evidence for the efficacy of behavioral approaches to the treatment and management of physical illness is mounting, as is the evidence for behavioral interventions for psychological disorders.
Pagoto, Sherry L.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Demographic Perspectives and De-escalation Challenges in Pediatric Emergency Care for Children with Special Health Care Needs

open access: yesJournal of Emergencies, Trauma and Shock
Introduction: Medical literature on emergency care for children with special healthcare needs (SHCNs) reports the inherent challenges in the managing of these children, like limited history, distress for patients and families, and unique management ...
Ninoshka Rivera-Koberstein   +2 more
doaj   +1 more source

Increasing the public health impact of evidence-based interventions in behavioral medicine: new approaches and future directions [PDF]

open access: yes, 2017
The dissemination and implementation of evidence-based behavioral medicine interventions into real world practice has been limited. The purpose of this paper is to discuss specific limitations of current behavioral medicine research within the context of
Sheinfeld Gorin, Sherri N.   +11 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Pharmacist-led implementation of a vancomycin guideline across medical and surgical units: impact on clinical behavior and therapeutic drug monitoring outcomes

open access: yesIntegrated Pharmacy Research and Practice, 2015
Cameron J Phillips,1–3 David L Gordon3,4 1Division of Pharmacy, SA Pharmacy, Flinders Medical Centre, Bedford Park, 2School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, 3Department of Microbiology and Infectious ...
Phillips CJ, Gordon DL
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Annual report to the Behavioral Health Partnership Oversight Council. 2010: Dec.

open access: yes, 2012
Annual; Began with 2009?; "Pursuant to CGS Section 17a-22m ..."--Letter of transmittal (publisher's Web site, viewed Apr. 1, 2011)
Connecticut Behavioral Health Partnership.
core   +1 more source

Envelhecimento bem-sucedido e as aprendizagens no esporte competitivo: uma forma de adaptação de atletas que praticam corrida

open access: yesRevista Brasileira de Geriatria e Gerontologia
Um arranjo conceitual que descreve o processo de envelhecimento bem-sucedido na perspectiva life-span é o modelo de estratégias denominado de seleção, otimização e compensação.
Sionara Tamanini de Almeida
doaj   +1 more source

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