Results 111 to 120 of about 3,282,089 (253)

Behavioral Queueing: An Agent Based Modeling Approach

open access: yes, 2012
Queueing research has a plethora of applications and has been an area of study spanning from telecommunications to economics. Traditionally, studies on queueing has mainly concentrated on design, performance and running of the service facility with ...
Sankaranarayanan, K.   +3 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Implementation of Alternating Direction Method of Multipliers for Solving Power Amplifier Linearization Problem: Theoretical Foundations and Proof of Concept

open access: yesIEEE Access
In this work, a formulation of alternating direction method of multipliers (ADMM) for addressing power amplifiers (PA) modeling and linearization problems is presented. The proposal consists on leveraging the implicit redundancy of the equations in order
Elias Marques-Valderrama   +2 more
doaj   +1 more source

Modelling Behavioral Heterogeneity. [PDF]

open access: yes
If one wants to get rid of the paradoxes pointed out by Hildenbrand (1998) and B. de Villemeur (1999), one needs to reformulate Grandmont's (1992) notion of behavioral heterogeneity such as to get exact insensitivity of the aggregate budget share ...
Isabelle MARET, Gael GIRAUD
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Quaternary Correlation Prediction Compensation for Heading Commands in Virtual Autopilot

open access: yesAerospace
Virtual commands serve as the essential framework for establishing interaction between the virtual pilot and the MCP in autopilot scenarios. Conventional proportional-integral-derivative (PID) controllers are insufficient to ensure accurate flight ...
Yutong Zhou, Shan Fu
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Behavioral Queueing: An Agent Based Modeling Approach

open access: yes, 2011
Queueing research has a plethora of applications and has been an area of study spanning from telecommunications to economics. Traditionally, studies on queueing has mainly concentrated on design, performance and running of the service facility with ...
Sankaranarayanan, K.   +3 more
core   +1 more source

A Multi-Level Modeling Framework for Detecting Hidden Risk Patterns in Complex Online Information Environments

open access: yesApplied Sciences
In the context of increasingly multi-source and complex online financial information dissemination, traditional single-modality risk detection methods are insufficient for effectively identifying highly concealed and coordinated financial risk behaviors.
Rong Fu   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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