Results 101 to 110 of about 3,317,573 (287)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Exploring the Perspectives of Lung Cancer Chemotherapy Patients on Self-Management: A Qualitative Interview Study Using the COM-B Model

Patient Preference and Adherence
Ruimei Jia,1,* Nina Xie,1,* Yue Li,2 Yu Zhang2 1School of Nursing, Shaanxi University of Chinese Medicine, Xianyang, People’s Republic of China; 2Department of Internal Medicine, Shaanxi Provincial Cancer Hospital, Xi’an, People’s ...
Jia R, Xie N, Li Y, Zhang Y
doaj  

A rank ordering and analysis of four cognitive-behavioral stress-management competencies suggests that proactive stress management is especially valuable

Scientific Reports
The main objective of this study was to determine the relative value of four cognitive-behavioral competencies that have been shown in empirical studies to be associated with effective stress management.
Robert Epstein, Jessica Aceret, Ciara Giordani, Vanessa R. Zankich, Lynette Zhang   +4 more
doaj   +1 more source

Asimovian Adaptive Agents

, 2011
The goal of this research is to develop agents that are adaptive and predictable and timely. At first blush, these three requirements seem contradictory.
Gordon, D. F.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Ethorobotic rats for rodent behavioral research: design considerations. [PDF]

Front Behav Neurosci, 2023
Siddall R.
europepmc   +1 more source

What are the Most Critical HR Capabilities and Competencies that are Emerging for the Future? [PDF]

, 2015
[Excerpt] What are most critical competencies that are emerging for HR professionals today? What capabilities are needed for HR leaders to advance forward in their careers? While there has been much research and emphasis on technical competencies.
Lee, Grace, Liu, Darren
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Reclaiming XAI as an Innovation in Healthcare: Bridging Rule-Based Systems

Algorithms
The adoption of explainable artificial intelligence (XAI) in healthcare has been increasingly framed as dependent on transparency, trustworthiness, and accountability.
Hanvedes Daovisan, Charin Suwanwong, Pitchada Prasittichok, Narulmon Prayai, Phaktada Choowan   +4 more
doaj   +1 more source

How Does the Cerebral Cortex Work? Developement, Learning, Attention, and 3D Vision by Laminar Circuits of Visual Cortex [PDF]

, 2003
A key goal of behavioral and cognitive neuroscience is to link brain mechanisms to behavioral functions. The present article describes recent progress towards explaining how the visual cortex sees.
Grossberg, Stephen
core   +1 more source