Results 71 to 80 of about 610,014 (250)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Unveiling the Impact of the Electrolyte's Counter Ions on Organic Electrochemical Transistor Performance

Advanced Electronic Materials
The effect of the electrolyte's counter‐ion in organic electrochemical transistors is often neglected. the influence of anions (i.e., counter ions) is investigated on organic electrochemical transistors (OECTs) with a PEDOT:PSS‐like semiconductor through
Sapir Bitton, Nir Tessler
doaj   +1 more source

At first sight: robots’ subtle eye movement parameters affect human attentional engagement, spontaneous attunement and perceived human-likeness

Paladyn, 2020
Human-robot interaction research could benefit from knowing how various parameters of robotic eye movement control affect specific cognitive mechanisms of the user, such as attention or perception.
Ghiglino Davide, Willemse Cesco, Tommaso Davide De, Bossi Francesco, Wykowska Agnieszka   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Planetary Health and Mental Health Nexus: Least Understood and Embraced in Policy Decisions

Annals of Global Health
Planetary health influences mental health and a better management of climate, biodiversity and pollution has co-benefits of improving mental health outcomes.
Manasi Kumar, Pim Cuijpers, Pushpam Kumar   +2 more
doaj   +1 more source

AI agent behavioral science

Humanities and Social Sciences Communications
Abstract Recent advances in large language models (LLMs) have enabled the development of AI agents that exhibit increasingly human-like behaviors, including planning, adaptation, and social dynamics across diverse, interactive, and open-ended scenarios.
Lin Chen 0002, Yunke Zhang, Jie Feng 0002, Haoye Chai, Honglin Zhang, Bingbing Fan, Yibo Ma, Shiyuan Zhang, Nian Li 0001, Tianhui Liu, Nicholas Sukiennik, Keyu Zhao, Yu Li 0022, Ziyi Liu, Fengli Xu, Yong Li 0008   +15 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source