Results 121 to 130 of about 2,057,463 (298)

The influence of motivational factors on choice behaviour

open access: yes, 2010
In this paper we investigate if and how motivational factors influence choice behaviour. We study four motivational factors: attitude towards car use, personal norm to reduce car use, car use habit, and perceived behavioural control to change car use to ...
Steg, L. (author)   +7 more
core  

The drivers of technology adoption on tobacco agribusiness in West Nusa Tenggara

open access: yesAgrointek
West Nusa Tenggara (NTB) is the third-largest tobacco-producing province in Indonesia. However, the dynamics of tobacco production tend to decline, one of which is due to its productivity and land area, which also tends to stagnate.
Eka Nurjati   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Influenza and pneumococcal vaccine hesitancy in the elderly population: results from two representative surveys in Germany

open access: yesBMC Public Health
Background The reasons for low influenza and pneumococcal vaccine acceptance in the elderly population are largely unknown – despite the great need of vaccines in this risk group.
Dorothee Heinemeier   +4 more
doaj   +1 more source

Senescence and costs of reproduction in the life history of a small precocial species

open access: yesEcology and Evolution, 2019
Species following a fast life history are expected to express fitness costs mainly as increased mortality, while slow‐lived species should suffer fertility costs.
Fritz Trillmich   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Stress in the spotlight: impacts of stress on learning and memory in a cichlid fish

open access: yesAnimal Cognition
Stress has been shown to both enhance and inhibit learning, which requires memory formation and memory retention. To date, the question of how stress influences learning and memory retention has been especially well studied in rodents and primates. Here,
Catalina Costiuc   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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