Results 141 to 150 of about 2,057,463 (298)

Early social experience influences the development of stereotypic behaviour in captive-born striped mice Rhabdomys.

, 2010
The early life experience of captive animals, in combination with their genetic inheritance, can predispose or promote the development of stereotypic behaviour in later life. To investigate the early social effects of weaning age and the presence/absence
Jones, M., Mason, G.J., Pillay, N.
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Integrating stereotypes and factual evidence in interpersonal communication

npj Science of Learning
Stereotypes can exert a powerful influence on our interactions with others, potentially leading to prejudice when factual evidence is ignored. Here, we identify neuroanatomical and developmental factors that influence the real-time integration of ...
Saskia B. J. Koch, Anna Tyborowska, Hannah C. M. Niermann, Antonius H. N. Cillessen, Karin Roelofs, Jana Bašnáková, Ivan Toni, Arjen Stolk   +7 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Effective lean-team interactions through leader values and members’ information sharing behaviour [PDF]

, 2016
Leaders are often blamed when lean work-floor initiatives fail. We hypothesise that leanteam leaders’ work values affect their team members’ information sharing behaviour and, through them, attain more effective team interactions. 429 survey responses of
van Dun, Desirée H., van Dun, Desirée H.; id_orcid, Wilderom, Celeste P.M.   +2 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Humans and traffic influence European wildcat behaviour in pastoral landscapes

Human activities and infrastructures can disturb wildlife and alter their behaviour by triggering antipredator responses such as changes in time allocation to different behaviours.
López Bao, José Vicente, Palomares, Francisco, Ruiz-Villar, Héctor, Morales-González, Ana, Palomares, F., Ruiz Villar, Héctor, Morales González, A., López-Bao, José V.   +7 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Children’s views on weight measurement and talking about weight

BMC Public Health
Background Parents are considered important in promoting children’s healthy weight, but express concern about how to talk to children about weight without harming their wellbeing. However, there is little research with children themselves as to what they
Ryan Herbert, Fiona Gillison, Elisabeth Grey, Abigail Hewitt, Alice Woods, Charlotte Jackson, Grace Wisbey, Jack Perks, Maddy Longhurst   +8 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source