Results 41 to 50 of about 774,595 (263)

Defensive freezing and its relation to approach–avoidance decision-making under threat

Scientific Reports, 2021
Successful responding to acutely threatening situations requires adequate approach–avoidance decisions. However, it is unclear how threat-induced states—like freezing-related bradycardia—impact the weighing of the potential outcomes of such value-based ...
Felix H. Klaassen, Leslie Held, Bernd Figner, Jill X. O’Reilly, Floris Klumpers, Lycia D. de Voogd, Karin Roelofs   +6 more
doaj   +1 more source

Cephalopod behaviour

Current Biology, 2023
Underlying all animal behaviors, from the simplest reflexive reactions to the more complex cognitive reasoning and social interaction, are nervous systems uniquely adapted to bodies, environments, and challenges of different animal species. Coleoid cephalopods - octopuses, squid, and cuttlefish - are widely recognized as the most behaviorally complex ...
Tamar, Gutnick, Daniel S, Rokhsar, Michael J, Kuba   +2 more
openaire   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Assessing the Emotional Response in Social Communication: The Role of Neuromarketing

Frontiers in Psychology, 2021
Social advertising is designed to have an impact on the behavior of the target audience to improve the welfare of both the individuals and the society.
Margherita Zito, Margherita Zito, Alessandro Fici, Alessandro Fici, Marco Bilucaglia, Marco Bilucaglia, Francesco S. Ambrogetti, Vincenzo Russo, Vincenzo Russo   +8 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A consumer register: an acceptable and cost-effective alternative for accessing patient populations

BMC Medical Research Methodology, 2016
Background Population-based registries are increasingly used to recruit patient samples for research, however, they have several limitations including low consent and participation rates, and potential selection bias.
Jamie Bryant, Rob Sanson-Fisher, Elizabeth Fradgley, Breanne Hobden, Alison Zucca, Frans Henskens, Andrew Searles, Brad Webb, Christopher Oldmeadow   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

‘Being There Together for Health’: A Systematic Review on the Feasibility, Effectiveness and Design Considerations of Immersive Collaborative Virtual Environments in Health Applications

Human Behavior and Emerging Technologies
Effectively using immersive multiuser environments for digital applications (via virtual, augmented and mixed reality technologies) beckons the future of healthcare delivery in the metaverse.
Tohid Zarei, Michelle Emery, Dimitrios Saredakis, Gun A. Lee, Ben Stubbs, Ancret Szpak, Tobias Loetscher   +6 more
doaj   +1 more source