Results 131 to 140 of about 2,982,565 (345)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Psychological distress and e-cigarette use among young Australians: An exploratory, qualitative study

open access: yesTobacco Induced Diseases
Introduction Emerging research suggests an association between psychological distress and e-cigarette use. However, our understanding of young adults’ experiences of this relationship is limited.
Mary-Ellen E. Brierley   +2 more
doaj   +1 more source

Physical activity and sedentary behaviour changes during and after cardiac rehabilitation: Can patients be clustered?

open access: gold, 2023
Marlou M. Limpens   +6 more
openalex   +2 more sources

Behaviour change intervention physical setting [PDF]

open access: hybrid, 2023
Behaviour Change Intervention Ontology (BCIO)
openalex   +1 more source

Challenges in Energy Awareness: a Swedish case of heating consumption in households [PDF]

open access: yes, 2013
An efficient and sustainable energy system is an important factor when minimising the environmental impact caused by the cities. We have worked with questions on how to construct a more direct connection between customers-­‐citizens and a provider of ...
Balksjö, Theresea   +2 more
core   +1 more source

Stability conditions under change of base field

open access: yes, 2011
We investigate the behaviour of Bridgeland stability conditions under change of base field with particular focus on the case of finite Galois extensions.
Bridgeland   +10 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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