Results 61 to 70 of about 2,982,565 (345)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Reversing the pipeline? Implementing public health evidence-based guidance in english local government

Implementation Science, 2017
Background In the UK, responsibility for many public health functions was transferred in 2013 from the National Health Service (NHS) to local government; a very different political context and one without the NHS history of policy and practice being ...
Lou Atkins, Michael P. Kelly, Clare Littleford, Gillian Leng, Susan Michie   +4 more
doaj   +1 more source

Applying the Behaviour Change Wheel to UK Local Authority Policy Documents: A Content Analysis in the Context of Financial Behaviour

Behavioral Sciences, 2023
Local authorities in the UK often try to improve their residents’ financial well-being by promoting changes in behaviour. The extent to which these behaviour change activities are based on relevant theory or evidence is unknown.
Zach Mills, Katryn Wright, Danielle D’Lima   +2 more
doaj   +1 more source

Cognitive biases, heuristics and decision-making in design for behaviour change [PDF]

, 2012
Copyright @ 2012 Social Science Electronic PublishingMuch human behaviour can be seen as decision-making, and so understanding and influencing those decision-making processes could be an important component in design for behaviour change.
Lockton, D
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Barriers and facilitators to consuming pulses: a qualitative exploration including effects of trying recipes at home

Journal of Nutritional Science
Pulses are a healthy, sustainable, low cost food, but consumption levels are low for a variety of reasons, including practical and cooking concerns. This work aimed to explore barriers and facilitators towards pulse consumption and increasing consumption,
B. Whittall, S. M. Warwick, M. Jackson, K. M. Appleton   +3 more
doaj   +1 more source

Interventions to improve appropriate antibiotic prescribing in long-term care facilities: a systematic review

BMC Geriatrics, 2020
Background Overuse of antibiotics has contributed to antimicrobial resistance; a growing public health threat. In long-term care facilities, levels of inappropriate prescribing are as high as 75%.
Elise Crayton, Michelle Richardson, Chris Fuller, Catherine Smith, Sunny Liu, Gillian Forbes, Niall Anderson, Laura Shallcross, Susan Michie, Andrew Hayward, Fabiana Lorencatto   +10 more
doaj   +1 more source

Developing and using ontologies in behavioural science: addressing issues raised [version 2; peer review: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2023
Ontologies are ways of representing aspects of the world in terms of uniquely defined classes of ‘entities’ and relationships between them. They are widely used in biological science, data science and commerce because they provide clarity, consistency ...
Nelli Hankonen, Robert West, Janna Hastings, Susan Michie, Marie Johnston, Alison J. Wright   +5 more
doaj   +1 more source

Prospects for radical emissions reduction through behaviour and lifestyle change [PDF]

, 2014
Over the past two decades, scholars and practitioners across the social sciences, in policy and beyond have proposed, trialled and developed a wide range of theoretical and practical approaches designed to bring about changes in behaviours and lifestyles
Alexander S., Anable J, Assadourian E., Bailey R, Bamberg S., Bergman N, Berker T., Cone JD, Crompton T., Crompton T., Dietz T, Dobson A., Dobson A., Foster B, Goodwin P, Gough I, Jackson T, Jackson T., Jackson T., Kasser T., Leiserowitz A, Lynas M., MacKay D., McCracken G., McKenzie-Mohr D., Merton RK., Miles S., Naish J., Newman P., Organisation for Economic Co-operation and Development (OECD), Parkhill KA, RAND Europe, Rorty R., Rowson J, Schneider F, Seyfang G., Spurling N, Swim J, Transport for London, UK Government, United Nations Environment Programme (UNEP), Whitmarsh L   +41 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source