Results 101 to 110 of about 359,828 (296)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Physical activity referral schemes: adherence and physical activity behaviour change [PDF]

It is well known that engaging in physical activity (PA) reduces the risk of developing non-communicable diseases and improves general health. However, at the time of this research, less than half of the UK population met the recommended levels of PA (DH,
Clarke, Kerry
core  

Self-reported sitting time and physical activity: interactive associations with mental well-being and productivity in office employees. [PDF]

, 2015
Background: Little is known about how sitting time, alone or in combination with markers of physical activity (PA), influences mental well-being and work productivity.
Fortuño Godes, Jesús, Bort-Roig, Judit, González-Suárez, Á, Ángel Manuel González-Suárez, Puig-Ribera, Anna, Laura Muñoz-Ortiz, Nicholas D Gilson, McKenna, J, González-Suárez, Angel M., Iván Martínez-Lemos, González-Suárez, Ángel Manuel, Bort Roig, Judit, Muñoz-Ortiz, L, Muñoz-Ortiz, Laura, Puig Ribera, Anna, Giné-Garriga, M, Giné-Garriga, Maria, Martínez-Lemos, Rodolfo Iván, Gilson, Nicholas D., Gilson, Nicholas D, Puig-Ribera, A, Martínez-Lemos, I, Martínez-Lemos, Iván, Jesús Fortuño, Fortuño, Jesús, González Suárez, Ángel Manuel, Gilson, ND, Manuel González-Suárez, Ángel, Anna Puig-Ribera, Maria Giné-Garriga, Fortuño, J, Judit Bort-Roig, Bort-Roig, J, Jim McKenna, McKenna, Jim   +34 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Increasing the frequency of physical activity very brief advice for cancer patients. Development of an intervention using the behaviour change wheel.

Public Health, 2016
BACKGROUND Being physically active has multiple benefits for cancer patients. Despite this only 23% are active to the national recommendations and 31% are completely inactive.
J. Webb, Jo Foster, E. Poulter
semanticscholar   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

‘EMERALD’ online early intervention programme for psychological well-being: A detailed description using the TIDieR checklist

Digital Health
Objective The rising prevalence of mental health symptoms brought on by the COVID19 pandemic led to the inception and development of EMERging Anxiety, Loneliness, Depression (EMERALD) well-being programme.
Monique Jones, Alexandra P Metse, Andrew Watkins, Daniel F Hermens, Christina Driver   +4 more
doaj   +1 more source

Spiritual Leadership, Religiosity, and Change Management Effectiveness: A Study in Educational Organisations

Edukasia
This study aimed to understand the influence of spiritual leadership and religiosity indicators on the effectiveness of change management in educational organisations as well as how spiritual leadership and religiosity interact in facilitating change in
Jahroni Jahroni, Sanaji Sanaji, Andre Dwijanto Witjaksono, Anang Kistyanto   +3 more
doaj   +1 more source

Supporting health behaviour change in chronic obstructive pulmonary disease with telephone health-mentoring: insights from a qualitative study

BMC Family Practice, 2012
Background Adoption and maintenance of healthy behaviours is pivotal to chronic disease self-management as this influences disease progression and impact.
Walters Julia A E, Cameron-Tucker Helen, Courtney-Pratt Helen, Nelson Mark, Robinson Andrew, Scott Jenn, Turner Paul, Walters E, Wood-Baker Richard   +8 more
doaj   +1 more source

Investigating changes in student mental health and help-seeking behaviour after the introduction of new well-being support services at a UK university

BJPsych Open
BackgroundGrowing numbers of students now seek mental health support from their higher education providers. In response, a number of universities have invested in non-clinical well-being services, but there have been few evaluations of these. This research addresses a critical gap in the existing literature.AimsThis study examined the impact of ...
Jacks Bennett, Claire M. A. Haworth, Judi Kidger, Jon Heron, Myles-Jay Linton, David Gunnell   +5 more
openaire   +4 more sources