Results 111 to 120 of about 359,828 (296)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Intervention development to reduce sedentary behaviour among adults: a qualitative investigation using the Behaviour Change Wheel

International Journal of Behavioral Nutrition and Physical Activity
Background Reducing prolonged sedentary behaviour is recommended to improve population health. The development of behaviour change interventions requires understanding context-specific determinants, which may differ across domains of transportation ...
Hannah Harsanyi, Nicole Slot, Reilly Parkinson, Andria R. Morielli, Apiramy Jeyapalan, Elizabeth Holmes, Susan Flynn, Tavis Campbell, Hude Quan, Yong Zeng, Jiami Yang, Shaminder Singh, Jennifer Vena, Stuart Biddle, Christine M. Friedenreich, Lin Yang   +15 more
doaj   +1 more source

Play to CHANGE: preliminary findings on using gamification to support a low-carbon transition

Journal of the British Academy
Project CHANGE (Curating a Human-centred Approach for net zero: Gamifying Energy-behaviour) investigates how gamification can support public engagement in domestic energy retrofit and encourage sustainable behaviours.
Max White, Jing Zhao, Neil Phillips
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Effectiveness and theory-based evaluation of a personalised digital intervention (EviBody®) for healthy and sustained lifestyle behaviours and well-being among adults: Study protocol for a real-world quasi-experimental study.

PLoS ONE
BackgroundDigital interventions offering behaviour change support are warranted to prevent and treat non-communicable diseases, and have been evaluated rigorously in controlled settings.
Jenny Rossen, Therese Anderbro, Susanne Andermo, Patrick Bergman, Maria Hagströmer, Mattias Jacobsson, Unn-Britt Johansson, Lena Kallings, Amanda Lönn, Callum Regan, Philip von Rosen   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Resisting organisational change? Psychological resilience and perceived organisational support as mediators in promoting psychological well-being and organisational citizenship behaviours

International Journal of Wellbeing
The increasing prevalence of global transformations has led to a surge in organisational changes worldwide. Consequently, the anticipation of employee resistance and its impact on organisational development has become a vital concern in the field of organisational psychology.
Nur Nabilah Muhammad Kamal, Guek Nee Ke, Zuhrah Beevi, Kenneth Leow   +3 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source