Results 81 to 90 of about 1,434,057 (290)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The use of the behaviour change wheel in the development of ParticipACTION’s physical activity app
Preventive Medicine Reports, 2020 The purpose of this study was to provide a detailed and systematic outline of how a theoretical behaviour change framework was applied in the development of ParticipACTION’s app to support a more active Canada.
Stephanie Truelove +4 more
doaj +1 more source
DNA unwinding heterogeneity by RecBCD results from static molecules able to equilibrate. [PDF]
, 2013 Single-molecule studies can overcome the complications of asynchrony and ensemble-averaging in bulk-phase measurements, provide mechanistic insights into molecular activities, and reveal interesting variations between individual molecules.
Baskin, Ronald J +2 more
core
Improve implementation of a novel paediatric therapy programme : taking theories of human behaviour into account [PDF]
, 2019 Background: ‘COPing with and CAring for Infants with special Needs’ (COPCA) is a novel family-centred early intervention programme in paediatric physiotherapy. COPCA differs from well-known approaches, e.g.
Akhbari Ziegler, Schirin +1 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
BMJ Open, 2020 Objective Educational, and audit and feedback interventions are effective in promoting health professional behaviour change and evidence adoption. However, we lack evidence to pinpoint which particular features make them most effective.
Nicole L Pratt +8 more
doaj +1 more source
What are the ‘active ingredients’ of interventions targeting the public's engagement with antimicrobial resistance and how might they work? [PDF]
, 2018 Objectives. Changing public awareness of antimicrobial resistance (AMR) represents a global public health priority. A systematic review of interventions that targeted public AMR awareness and associated behaviour was previously conducted.
Davis, Mark +9 more
core +4 more sources
D6.2 Behavioural change techniques for hackAIR community
, 2018 The present document is a deliverable of the hackAIR project, funded by the European Commission under the Horizon 2020 programme. This deliverable is concerned with the development of an effective strategy for promoting the adoption and usage of the hackAIR platform.
Hoelck, Katharina +5 more
openaire +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Public Health, 2015 Background Children spend a large amount of their time in obligatory seated school lessons, with notable effects on health and cognitive outcomes. A common issue reported by teachers is a lack of time to incorporate physical activity into the school day
Emma Norris +3 more
doaj +1 more source