YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Metal Packaging: From Monolithic Containers to Hybrid Architectures. [PDF]
Pagnotta L.
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Effects of Sand-Coated and Ribbed GFRP Bars in Hybrid GFRP-Steel-Reinforced Concrete Beams. [PDF]
Devaraj R, Olofinjana A, Gerber C.
europepmc +1 more source
Low-Temperature Lignin-Derived Carbon Electrodes Enabled by a Natural Casein Binder for Lithium-Ion, Sodium-Ion Batteries and Supercapacitors. [PDF]
Gross X +4 more
europepmc +1 more source
Using systems archetypes to understand system behaviour and identify leverage points for change in local obesity prevention in The Netherlands. [PDF]
O'Mara J +4 more
europepmc +1 more source
Performance of High-Workability Mortars Incorporating Metakaolin as a Partial Cement Replacement. [PDF]
Garcia-Troncoso N +3 more
europepmc +1 more source
A hybrid RL-GA-LSTM-AE framework for energy-aware and SLA-driven task scheduling in cloud computing environments. [PDF]
Narsimhulu B, Kumar TS.
europepmc +1 more source

