Results 61 to 70 of about 58,156 (257)

Stiffness-Displacement Correlation from the RC Shear Wall Tests of the SAFE Program: Derivation of a Capacity Line Model

open access: yesAdvances in Materials Science and Engineering, 2016
The response of 13 reinforced concrete shear walls submitted to successive seismic tests has been postprocessed to produce time histories of secant stiffness and displacement oscillation amplitude.
Francisco J. Molina   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Demand response aggregator coordinated two‐stage responsive load scheduling in distribution system considering customer behaviour

open access: yesIET Generation, Transmission & Distribution, 2017
A demand response aggregator (DRA)‐coordinated load scheduling in distribution system with responsive loads is presented. The mutually exclusive scheduling objectives of demand response provider (DRP) and distribution network operator (DNO) are optimally compromised by DRA through incentive‐based participation strategies of DRPs.
Lokesh Kumar Panwar   +4 more
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Seismic Retrofit of a Multispan Prestressed Concrete Girder Bridge with Friction Pendulum Devices

open access: yesShock and Vibration, 2018
The paper deals with the proposal and application of a procedure for the seismic retrofit of an existing multispan prestressed concrete girder bridge defined explicitly for the use of friction pendulum devices as an isolation system placed between piers ...
Alberto Maria Avossa   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Rebound behaviour of uncoordinated EMS and their impact minimisation

open access: yesIET Smart Grid, 2019
In this paper, the impacts of uncoordinated energy management systems (EMS), with a rebound effect, on a renewable energy-dependent microgrid are discussed and feasible solutions are presented. Two different approaches, i.e.
Khizir Mahmud   +3 more
doaj   +1 more source

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