Results 21 to 30 of about 828 (179)

Virulence Traits and Population Genomics of the Black Yeast Aureobasidium melanogenum

Journal of Fungi, 2021
The black yeast-like fungus Aureobasidium melanogenum is an opportunistic human pathogen frequently found indoors. Its traits, potentially linked to pathogenesis, have never been systematically studied. Here, we examine 49 A.
Anja Černoša, Xiaohuan Sun, Cene Gostinčar, Chao Fang, Nina Gunde-Cimerman, Zewei Song   +5 more
doaj   +1 more source

Enhancement of de novo sequencing, assembly and annotation of the Mongolian gerbil genome with transcriptome sequencing and assembly from several different tissues

BMC Genomics, 2019
Background The Mongolian gerbil (Meriones unguiculatus) has historically been used as a model organism for the auditory and visual systems, stroke/ischemia, epilepsy and aging related research since 1935 when laboratory gerbils were separated from their ...
Shifeng Cheng, Yuan Fu, Yaolei Zhang, Wenfei Xian, Hongli Wang, Benedikt Grothe, Xin Liu, Xun Xu, Achim Klug, Elizabeth A. McCullagh   +9 more
doaj   +1 more source

Excavation of underground research laboratory ramp in granite using tunnel boring machine: Feasibility study

Journal of Rock Mechanics and Geotechnical Engineering, 2020
Underground research laboratory (URL) plays an important role in safe disposal of high-level radioactive waste (HLW). At present, the Xinchang site, located in Gansu Province of China, has been selected as the final site for China’s first URL, named ...
Hongsu Ma, Ju Wang, Ke Man, Liang Chen, Qiuming Gong, Xingguang Zhao   +5 more
doaj   +1 more source

Detection of fetal trisomy and single gene disease by massively parallel sequencing of extracellular vesicle DNA in maternal plasma: a proof-of-concept validation

BMC Medical Genomics, 2019
Background During human pregnancy, placental trophectoderm cells release extracellular vesicles (EVs) into maternal circulation. Trophoblasts also give rise to cell-free DNA (cfDNA) in maternal blood, and has been used for noninvasive prenatal screening ...
Weiting Zhang, Sen Lu, Dandan Pu, Haiping Zhang, Lin Yang, Peng Zeng, Fengxia Su, Zhichao Chen, Mei Guo, Ying Gu, Yanmei Luo, Huamei Hu, Yanping Lu, Fang Chen, Ya Gao   +14 more
doaj   +1 more source

Homologous recombination deficiency status predicts response to platinum-based chemotherapy in Chinese patients with high-grade serous ovarian carcinoma

Journal of Ovarian Research, 2023
Background Homologous Recombination Deficiency (HRD) is a predictive biomarker for ovarian cancer treated with PARP inhibitors or for breast cancer treated with first-line platinum-based chemotherapy.
Zheng Feng, Di Shao, Yuhang Cai, Rui Bi, Xingzhu Ju, Dongju Chen, Chengcheng Song, Xiaojun Chen, Jin Li, Na An, Yunjin Li, Qing Zhou, Zhihui Xiu, Shida Zhu, Xiaohua Wu, Hao Wen   +15 more
doaj   +1 more source

Spatial transcriptome unveils a discontinuous inflammatory pattern in proficient mismatch repair colorectal adenocarcinoma

Fundamental Research, 2023
The preexistence of immune cells in the tumor microenvironment substantiates the efficacy of immunotherapy in cancer patients. Although the complex intratumoral immune heterogeneity has been extensively studied in single cell resolution, hi-res spatial ...
Rongxin Zhang, Yu Feng, Wenjuan Ma, Yanying Guo, Mei Luo, Young Li, Yupeng Zang, Xuan Dong, Shixun Lu, Qiang Guo, Qumiao Xu, Huanyi Chen, Yijian Li, Longqi Liu, Ao Chen, Gong Chen, Xun Xu   +16 more
doaj   +1 more source

Experimental and Numerical Study on Hydromechanical Coupled Deformation Behavior of Beishan Granite considering Permeability Evolution

Geofluids, 2020
Beishan granite is a potential host rock for a high-level radioactive waste (HLW) repository in China. Understanding the hydromechanical (HM) behavior and permeability evolution of Beishan granite is important for the HLW repository safety.
Z. H. Wang, W. G. Ren, Y. L. Tan, Heinz Konietzky   +3 more
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Characterization and description of Faecalibacterium butyricigenerans sp. nov. and F. longum sp. nov., isolated from human faeces

Scientific Reports, 2021
Exploiting a pure culture strategy to investigate the composition of the human gut microbiota, two novel anaerobes, designated strains AF52-21T and CM04-06T, were isolated from faeces of two healthy Chinese donors and characterized using a polyphasic ...
Yuanqiang Zou, Xiaoqian Lin, Wenbin Xue, Li Tuo, Ming-Sheng Chen, Xiao-Hui Chen, Cheng-hang Sun, Feina Li, Shao-wei Liu, Ying Dai, Karsten Kristiansen, Liang Xiao   +11 more
doaj   +1 more source

Petrogenesis and geological implications of the qiyishan triassic granitoids in east Beishan orogen, inner Mongolia, NW China: evidence from geochronology, geochemistry and Nd-Hf isotopes

Frontiers in Earth Science, 2023
The Qiyishan deposit is a large-scale Rb polymetallic deposit in the Beishan orogen. However, there remain debates regarding its metallogenic age and tectonic setting.
Ruiqin Liu, Chao Chen, Xinbiao Lv, Zhongcheng Zhang, Banxiao Ruan, Shanming Zhang, Erhong Hu   +6 more
doaj   +1 more source

Identification and Evolutionary Characteristics of Major Fractures in Beishan Granite

Applied Sciences, 2023
Identification of major fractures is a common problem in underground engineering. Research on the identification and evolutionary characteristics of major fractures are mainly based on high-level waste underground repositories. In this paper, a triaxial acoustic emission (AE) experiment was carried out, and methods such as fractal theory and machine ...
Chaosheng Wang, Hao Wan, Weiguang Ren, Jianjun Ma   +3 more
openaire   +2 more sources