Results 31 to 40 of about 828 (179)

Therapeutic potential of CRISPR/Cas9 gene editing in engineered T‐cell therapy

open access: yesCancer Medicine, 2019
Cancer patients have been treated with various types of therapies, including conventional strategies like chemo‐, radio‐, and targeted therapy, as well as immunotherapy like checkpoint inhibitors, vaccine and cell therapy etc.
Qianqian Gao   +6 more
doaj   +1 more source

Comparative Analyses of 3,654 Plastid Genomes Unravel Insights Into Evolutionary Dynamics and Phylogenetic Discordance of Green Plants

open access: yesFrontiers in Plant Science, 2022
The plastid organelle is essential for many vital cellular processes and the growth and development of plants. The availability of a large number of complete plastid genomes could be effectively utilized to understand the evolution of the plastid genomes
Ting Yang   +16 more
doaj   +1 more source

Evaluation on Soil Quality Changes due to Land from Hill Cutting in Beishan Mountain in Lanzhou City

open access: yesShuitu baochi tongbao, 2023
[Objective] The soil quality changes caused by land from hill citting in Beishan Mountain in Lanzhou City were assessed in order to provide a scientific basis and suggestions for land-cutting and land-reclamation projects and ecological benefit ...
Ren Xiuzi   +3 more
doaj   +1 more source

Experimental study on thermo-mechanical properties of Beishan granite under mild temperature

open access: yesCase Studies in Thermal Engineering, 2022
Temperature is believed to have an important influence on the mechanics behavior of granite. To investigate thermo-mechanical properties of Beishan granite, the host rock of China's preselected underground laboratory of high-level radioactive waste (HLW)
Yunlei Tian   +5 more
doaj   +1 more source

Geochronological and Geochemical Constraints on the Petrogenesis of Permian Dolerite Dyke Swarms in the Beishan Orogenic Belt, NW China

open access: yesFrontiers in Earth Science, 2021
Extensive Early Permian mafic-ultramafic intrusions, doleritic dykes, and basalts crop out within the Beishan area, southern Central Asian Orogenic Belt (CAOB).
Gang Xu   +6 more
doaj   +1 more source

Distribution, characteristics, ages, and tectonic environments of ductile shear zones in the Beishan orogenic belt

open access: yesDizhi lixue xuebao
Objective  The Beishan occupies a pivotal position between the eastern and western segments of the Central Asian Orogenic Belt (CAOB). Although numerous ductile shear zones have been identified in this area, they have received limited attention, leading ...
ZHANG Jin   +7 more
doaj   +1 more source

Single-cell transcriptomic landscape identifies the expansion of peripheral blood monocytes as an indicator of HIV-1-TB co-infection

open access: yesCell Insight, 2022
Certain circulating cell subsets are involved in immune dysregulation in human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) co-infection; however, the characteristics and role of these subclusters are unknown.
Qinglong Guo   +17 more
doaj   +1 more source

The Effect of Unloading Path on the Time-Dependent Behavior of Beishan Granite

open access: yesLithosphere, 2022
Abstract Understanding the time-dependent characteristics of Beishan granite after excavation is critically important for the long-term stability and disaster control of the high-level radioactive waste repository. In this context, a series of creep tests under different unloading paths are designed to simulate the time-dependent ...
Peiyang Yu   +4 more
openaire   +2 more sources

Fugacium Spliced Leader Genes Identified from Stranded RNA-Seq Datasets

open access: yesMicroorganisms, 2019
Trans-splicing mechanisms have been documented in many lineages that are widely distributed phylogenetically, including dinoflagellates. The spliced leader (SL) sequence itself is conserved in dinoflagellates, although its gene sequences and arrangements
Yue Song   +7 more
doaj   +1 more source

Experimental study on mechanical properties of Beishan granite in the mild temperature range

open access: yesCase Studies in Thermal Engineering, 2023
The response of mechanical property to temperature, especially in the mild temperature range, is important for the high-level waste (HLW) geological disposal engineering.
Guibin Wang, Shiwan Chen, Kexun Zheng
doaj   +1 more source

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