Results 221 to 230 of about 1,868,552 (400)

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

open access: yesAdvanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang   +10 more
wiley   +1 more source

From Solution to Surface: How the Catalytic Environment Modulates Peptide Bond Cleavage by Metal‐Oxo Cluster Nanozymes

open access: yesAdvanced Science, EarlyView.
Comparison of homogeneous Hf12(sol) and heterogeneous Hf12(precip) metal‐oxo clusters enables investigation of how solubility influences nanozymatic reactivity and selectivity toward proteolysis, without introducing confounding factors from differences in cluster identity.
Kilian Declerck   +7 more
wiley   +1 more source

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

open access: yesAdvanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács   +9 more
wiley   +1 more source

A phase IV prospective study of efficacy and safety of ribociclib and letrozole as first-line therapy in older women (≥70 years) with hormone receptor-positive HER2-negative advanced breast cancer: the RibOB study. [PDF]

open access: yesESMO Open
Van Houdt M   +15 more
europepmc   +1 more source

Health literacy and the use of healthcare services in Belgium

open access: yesJournal of Epidemiology and Community Health, 2016
Jessica Vandenbosch   +5 more
semanticscholar   +1 more source

Country Report Belgium [PDF]

open access: yes, 2008
van Puyenbroeck, Laurens   +1 more
core  

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

open access: yesAdvanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin   +16 more
wiley   +1 more source

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