Results 31 to 40 of about 1,651,452 (304)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Un modelo en derecho comparado: el régimen lingüístico belga en el ámbito judicial
This article analyzes the linguistic regime in Belgium by focusing on the judiciary. Formally, it is structured in four headings. In the first one we introduce the study and justify its interest from a comparative approach.
Anna M. Pla Boix
doaj +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
In light of the recent steps Belgium has made towards reconciling with its colonial history in Congo (e.g., the King’s letter of regret, and the removal of some colonial statues), we examined how Belgians differ in their attitudes towards an official ...
Jasper Van Assche +3 more
doaj +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
"LETTER TO THE KING" BY JULES DESTRY: FROM SEPARATISM TO UNITARISM IN BELGIUM
Contradictions between the regions of Belgium - Wallonia and Flanders - have a long history associated with uneven political, economic and cultural development of the territories, which in 1830 became parts of an independent state, the Kingdom of Belgium.
E. V. Ermakova
doaj +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Who is Responsible for Instability in the Democratic Republic of Congo?
The research focuses on the problem of military-political instability in the Democratic Republic of the Congo experiencing continued armed conflict for a long time.
G. M. Sidorova
doaj +1 more source
Brief Description of German and Other Germanic Language Varieties on the Territory of Wallonia
Introduction. The article considers the official and regional Germanic language varieties of Wallonia. As researchers mainly focus on the confrontation of the French and Dutch parts of Belgium when analyzing sociolinguistic processes in the country ...
E. S. Alekseenko, L. A. Ulianitckaia
doaj +1 more source

