Results 91 to 100 of about 3,586,308 (370)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Suppressed Belief

open access: yesTHEORIA, 2009
Moran's revised conception of conscious belief requires us to reconceptualise suppressed belief. The work of Merleau-Ponty offers a way to do this. His account of motor-skills allows us to understand suppressed beliefs as pre-reflective ways of dealing with the world.
openaire   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Displacement of Myths in The Da Vinci Code and The Krishna Key: A Comparative Study [PDF]

open access: yesAnnals of Philosophy, Social and Human Disciplines, 2016
This comparative analysis of The Da Vinci Code and The Krishna Key by Ashwin Sanghi attempts to scrutinize the portrayal of institutionalized religions in the novels. The paper endeavours to trace the process of demythologization in relation to organized
M. JAYABHARATHI
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Connecting the dots: Illusory pattern perception predicts belief in conspiracies and the supernatural

open access: yesEuropean Journal of Social Psychology, 2017
A common assumption is that belief in conspiracy theories and supernatural phenomena are grounded in illusory pattern perception. In the present research we systematically tested this assumption.
Jan‐Willem van Prooijen   +2 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Hegel and postmodernism: A reengagement [PDF]

open access: yesFilozofija i Društvo
This paper introduces and addresses fresh perspectives in the engagement between Hegel and his postmodern critics and detractors. The first part of the paper examines some of the central discussions on postmodernity, specifically in the works of
Hristov Đorđe, Hrnjez Saša
doaj   +1 more source

Appropriate Belief Without Evidence [PDF]

open access: yes, 2015
In this paper I defend a version of Wittgensteininan contextualism. This is a view about justification on which some beliefs are epistemically appropriate because evidence cannot be adduced in their favour.
Ashton, Natalie Alana
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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