Results 41 to 50 of about 760,634 (252)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Discourse Contestation in Islamic Studies: A Critical Analysis of Stefan Reichmuth's Orientalist Approach and Muslim Intellectual Responses

Universal Journal of History and Culture
Islamic studies conducted by orientalists often face criticism because they are considered to have an epistemological bias that tends to view Islam from an external and secular perspective.
Siti Atieqoh, Daud Rasyid, Retno Kartini Savitaningrum Imansah, Lallo Hamid, Aisyah Daud Rasyid   +4 more
doaj   +1 more source

Perception, attitudes, knowledge of using complementary and alternative medicine for cancer patients among healthcare professionals: A mixed‐methods systematic review

Cancer Medicine, 2023
Background With the rapid increase in the prevalence of cancer worldwide, the utilization of complementary and alternative medicine (CAM) has increased among cancer patients.
Bo‐Young Youn, Jie‐Won Cha, Sungsu Cho, So‐Mi Jeong, Hyo‐Jung Kim, Seong‐Gyu Ko   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hippocampus-targeted BDNF gene therapy to rescue cognitive impairments of Alzheimer's disease in multiple mouse models

Genes and Diseases
Brain-derived neurotrophic factor (BDNF) can protect neurons from apoptosis and maintain normal synaptic structures, indicating a significant potential for Alzheimer's disease (AD) treatment.
Siqi Tang, Wenshu Luo, Shihao Wu, Meng Yuan, Jiashuo Wen, Guoshen Zhong, Leshan Shen, Wei Jiang, Cheng Cheng, Xia Wu, Xiao Xiao   +10 more
doaj   +1 more source

Post COVID-19, still wear a face mask? Self-perceived facial attractiveness reduces mask-wearing intention

Frontiers in Psychology, 2023
With the emerging post-COVID era, wearing face masks has become a domain of personal choice. Then, who wants to continue wearing a mask when it is no longer mandatory?
Seung Eun Cha, Xyle Ku, Incheol Choi, Incheol Choi   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Truth: the aim and norm of belief [PDF]

, 2013
Invited contribution to The Aim of Belief, a special issue of Teorema, guest-edited by J ...
Whiting, Daniel
core   +1 more source

Legal Aspects of the use of Force and Reasonableness Standard

Journal of Danubian Studies and Research, 2022
In the social and political environment, regardless of jurisdiction, the use of force and the intervention of law enforcement agencies, especially of the police force, is current issue, and the topic of adequate intervention - a topic of debate.
Andrei Pântea, Serghei Pântea
doaj