Results 91 to 100 of about 198,449 (262)

On the implementation of the belief change operators

open access: yesJournal of Computer Science and Technology, 2000
In this article we will introduce certain considerations that must be taken into account while implementing the change operations of the belief change theory.
Marcelo Alejandro Falappa   +1 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

“Can you Hear me?” Change of technology commitment during the first two semesters under COVID-19

open access: yesDiscover Education
The COVID-19 pandemic challenged universities to maintain teaching, leading to online classes becoming the standard teaching mode and accelerating digitalization.
Leonard Puderbach   +2 more
doaj   +1 more source

CHANGING PETROGLYPHS – CHANGING BELIEFS?

open access: yesЗнаки и образы в искусстве каменного века. Международная конференция. Тезисы докладов [Электронный ресурс], 2019
This paper takes a starting point in the periodic division of the approximately 6000 petroglyphs made during the last 5000 years BC in a North Norwegian fjord area, the ethnography of changing the hunter-fishing- pastoral Sami population in Fennoscandia and the documentation of their traditional system of belief as documented during the 16th 18th ...
openaire   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Epistemological Sensitization as a Short-Term Intervention to Change Epistemological Beliefs—Is It Effective or Not?

open access: yesEducation Sciences
This study investigates the effects of an epistemological sensitization on domain-specific epistemological beliefs. An epistemological sensitization is a short-term intervention that presents a domain’s epistemological features to elicit epistemological ...
Eric Klopp, Johanna Gathen, Robin Stark
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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