Results 91 to 100 of about 5,670,665 (286)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Correlation coefficient measurement for conflict evidence
Tongxin xuebao, 2018 The complex battlefield environment increases the uncertainty of reconnaissance information processing, so the uncertain information processing is investigated, especially the conflict evidence measurement, based on the belief functions.
Guidong SUN +3 more
doaj
Frontiers in PsychologyIntroductionResearch has indicated that language and executive function relate closely to first-order false belief reasoning, yet their roles in second-order false belief reasoning are under-explored, and their interplay in theory of mind development ...
Honglan Li, Man-Tak Leung
doaj +1 more source
Belief change in branching time: AGM-consistency and iterated revision [PDF]
We study belief change branching-time structures. First, we identify a property of branching-time frames that is equivalent to AGM-consistency, which is defined as follows. A frame is AGM-consistent if the partial belief revision function associated with
Giacomo Bonanno
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Belief-based action prediction in preverbal infants [PDF]
, 2014 Successful mindreading entails both the ability to think about what others know or believe, and to use this knowledge to generate predictions about how mental states will influence behavior. While previous studies have demonstrated that young infants are
Southgate, Victoria +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
INTRODUCTION TO THE SEMANTICS OF BELIEF AND COMMON BELIEF [PDF]
We provide an introduction to interactive belief systems from a qualitative and semantic point of view. Properties of belief hierarchies are formulated locally.
Klaus Nehring, Giacomo Bonanno
core