Results 81 to 90 of about 5,670,665 (286)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Correlation Between Family Functioning and Health Beliefs in Patients with Stroke in Beijing, China

open access: yesJournal of Multidisciplinary Healthcare, 2023
Lingli Zhang,1,* YaoYa Shu,2,* Chunjie Han,3,* Jihong Liu1 1Department of Neurology, Beijing Luhe Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Nursing, The Second Affiliated Hospital of Nanchang ...
Zhang L, Shu Y, Han C, Liu J
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Path to Fully Representational Theory of Mind: Conceptual, Executive, and Pragmatic Challenges

open access: yesFrontiers in Psychology, 2020
Although an explicit Theory of Mind (ToM) has been found to develop around 4 years of age in Western societies, recent work showing that 4- and 5-year-olds fail modified versions of False Belief tasks as well as seemingly easier True Belief tasks calls ...
Annelise Pesch   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Distributed combination of belief functions

open access: yesInformation Fusion, 2021
Abstract We consider the problem of combining belief functions in a situation where pieces of evidence are held by agents at the node of a communication network, and each agent can only exchange information with its neighbors. Using the concept of weight of evidence, we propose distributed implementations of Dempster’s rule and the cautious rule ...
openaire   +3 more sources

A Model of Minimal Probabilistic Belief Revision [PDF]

open access: yes
A probabilistic belief revision function assigns to every initial probabilistic belief and every observable event some revised probabilistic belief that only attaches positive probability to states in this event.
Perea,Andrés
core  

What Do Executive Factors Contribute to the Failure on False Belief Tasks by Children with Autism? [PDF]

open access: yes, 1999
As children with autism have pervasive executive difficulties it is necessary to determine whether these contribute to their often-reported failure on the false belief task. Failure on this task is frequently taken to diagnose the lack of a ``theory of
Russell, J.   +2 more
core   +1 more source

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