Results 41 to 50 of about 148,608,386 (232)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Bystander behavior in school bullying and multidimensional belief in a just world
Frontiers in EducationIntroductionBullying is a significant issue that harms children’s health and infringes on their right to education. Understanding the mechanisms of bullying, preventing it, and implementing appropriate interventions are essential for education.
Kumpei Mizuno
doaj +1 more source
Frontiers in Psychology, 2021 The purpose of this study was to verify the relationships among concealment tendencies, illness attitudes, belief in a just world, and cognitive flexibility. The participants were 418 Korean and 400 Chinese adults.
Kyung Hwan Cha +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Personal belief in a just world and mental health
Acta PsychologicaPersonal Belief in a Just World (PBJW) has been associated with better mental health outcomes; however, the mechanisms underlying this relationship remain insufficiently understood.
Lisa Schniesko, Mike Lüdmann
doaj +1 more source
BMC Geriatrics, 2022 Background With an increasingly ageing population worldwide, the predominant attitude towards ageing is still negative. Negative stereotypes have detrimental effects on individuals’ physical and mental health.
Madeleine Thelu +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2017 School attacks against children seriously threaten the belief that the world is a just place, in which good people get rewarded and bad people get punished.
Wu, Michael Shengtao +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source