Results 51 to 60 of about 148,608,386 (232)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Is Belief in a Just World Rational?
, 1998 To estimate the relationship between the belief in a just world and irrational thinking, 62 undergraduates completed the Jones Irrational Beliefs Test and the Multidimensional Belief in a Just World Scale. It was hypothesized that belief in a just world
Deborah A. Stowers, Mark W. Durm
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Less Illusion of a Just World in People with Formally Diagnosed Autism and Higher Autistic Traits [PDF]
, 2021 People differ in how strongly they believe that, in general, one gets what (s)he deserves (i.e., individual differences in the general belief in a just world). In this study (N = 588; n = 60 with a formal autism diagnosis), whether or not autistic people
Bertrams, Alex
core +2 more sources
Psychology Research and Behavior Management, 2023 Aichun Liu,1,2 Zhaojun Chen,1,3 Shichao Wang,1 Jianpeng Guo,1 Lin Lin3 1Institute of Education, Xiamen University, Xiamen, People’s Republic of China; 2Mental Health Education and Counseling Center, Nanjing Institute of Tourism and Hospitality, Nanjing ...
Liu A, Chen Z, Wang S, Guo J, Lin L
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Racial discrimination and belief in a just world: Police violence against teenagers in Brazil
, 2018 Discrimination against black people is analyzed based on tolerance for police violence, support for lowering the age of criminal responsibility, and support for the payment of compensation by the police to teenage offenders. Three studies were conducted,
José Luis Álvaro Estramiana +9 more
core +1 more source