Results 91 to 100 of about 2,498,764 (311)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Exploring Body Comparison Tendencies: Women Are Self-Critical Whereas Men Are Self-Hopeful [PDF]
Our study examined similarities and differences in women’s and men’s comparison tendencies and perfection beliefs when evaluating their face, body shape, and physical abilities, as well as how these tendencies and beliefs relate to their body esteem ...
Aebly, Megan +5 more
core +1 more source
Responding to the Religious Reasons of Others: Resonance and Non-Reducitve Religious Pluralism [PDF]
Call a belief ”non-negotiable’ if one cannot abandon the belief without the abandonment of one’s religious perspective. Although non-negotiable beliefs can logically exclude other perspectives, a non-reductive approach to religious pluralism can help to ...
Legenhausen, Muhammad
core +1 more source
Korean Americans' Beliefs about Colorectal Cancer Screening
Purpose: The purpose of this study was to assess Korean Americans' (KAs) health and cultural beliefs about colorectal cancer (CRC) and their CRC screening utilization in order to understand how health and cultural beliefs play a role in CRC screening ...
Shin-Young Lee, PhD, RN +1 more
doaj +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Contemporary societies are often "polarized", in the sense that sub-groups within these societies hold stably opposing beliefs, even when there is a fact of the matter.
O'Connor, Cailin, Weatherall, James Owen
core +3 more sources
This article aims to see the extent of the traditional beliefs of the Toba Batak people and their relevance in people's lives in the Lake Toba area.
Harisan Boni Firmando
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Towards an ontology of common sense [PDF]
Philosophers from Plotinus to Paul Churchland have yielded to the temptation to embrace doctrines which contradict the core beliefs of common sense. Philosophical realists have on the other hand sought to counter this temptation and to vindicate those ...
Smith, Barry
core
Should religious believers proportion their religious beliefs to their evidence? They should: Religious faith is better, ceteris paribus, when the beliefs accompanying it are evidence-proportioned.
Dormandy, Katherine
core +1 more source

