Results 81 to 90 of about 951,315 (252)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
What are the beliefs of women who lead?
, 2017 The focus of this study was to discover what beliefs women leaders hold and provide an opportunity to share their advice with future leaders. Adhering to Royal Roads University Research Ethics policies, ten women, from private sector organizations, who ...
Sheppard, Cary Maria
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Aggregation of Heterogeneous Beliefs and Asset Pricing: A Mean-Variance Analysis [PDF]
The aim of this paper is to show, within the mean-variance framework, how the market belief can be constructed as the result of the aggregation of heterogeneous beliefs and how the market equilibrium prices of risky assets can thus be determined.
Roberto Dieci, Carl Chiarella, Tony He
core
Daniel Fabre et le messager des âmes
L'Atelier du CRH, 2017 This essay in memory of Daniel Fabre is devoted to the communication he gave in the conference "Death Today" held in Saint-Maximin in July 1981. In his contribution Daniel Fabre analyzed the importance and the role played by the "messengers of the dead ...
Roger Chartier
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Portfolio Analysis and Zero-Beta CAPM with Heterogeneous Beliefs [PDF]
With the standard mean variance framework, by assuming heterogeneity and bounded rationality of investors, this paper examines their impact on the market equilibrium and implications to the portfolio analysis.
Xue-Zhong He, Lei Shi
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
FALLING DOMINOS OR THE ROLE OF GEOGRAPHIC MENTAL MAPS IN FOREIGN POLICY
European Journal of Geography, 2023 Geographic mental maps are commonly used to explain foreign policy behaviour of political decision-makers. However, despite the proliferation of their usage, a theoretical account of how mental maps influence foreign policy is still lacking. The current
Luis M. DA VINHA
doaj