Results 91 to 100 of about 125 (122)

Passenger variants as pan‐clonal markers of pediatric AML: Implications for molecular MRD

HemaSphere, Volume 10, Issue 8, August 2026.
Abstract A streamlined, sensitive, and universal molecular method for MRD detection in pediatric AML remains an unmet clinical need. Here, we propose a novel approach based on tracking somatic non‐coding passenger variants. Using whole‐genome sequencing (WGS) of diagnostic bone marrow DNA, we identify patient‐specific somatic passenger variants, which ...
Ruth Shiloh, Dana Dayan, Ifat Geron, Maor Cohen, Tamar Feuerstein, Jorge Cano‐Nistal, Nurit Gal‐Mark, Shlomit Barzilai‐Birenboim, Dafna Gaash, Michal Hameiri‐Grossman, Avraham Kahan, Jamal Mahajna, Nino Oniashvili, Hava Rosenfeld, Dan Scharf, Keren Shichrur, Elena Shinderman‐Maman, Sarah Elitzur, Yehudit Birger, Shai Izraeli, Yosef E. Maruvka   +20 more
wiley   +1 more source

Phenolic composition and multi‐target bioactivities of Globularia alypum extracts across seasons

JSFA reports, Volume 6, Issue 8, Page 314-330, August 2026.
Abstract Background This study investigates the influence of seasonal variation on the phytochemical profile and biofunctional activities of ethanolic leaf extracts from Globularia alypum. Leaves collected across four seasons were extracted with a hydroethanolic solvent (80:20, v/v) and analyzed by LC‐ESI‐MS/MS.
Mohammed Messaoudi, Khalil Guelift, Mokhtar Benmohamed, Khaled Kherraz, Latifa Khattabi, Afaf Khadra Bendrihem, Khaled Aggoun, Barbara Sawicka, Lilya Harchaoui, Mohamed Amine Ferhat, Salah Neghmouche Nacer, Stefania Garzoli   +11 more
wiley   +1 more source

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source

A Comparative dose and image quality assessment of a portable, multi‐modality extremity imaging system for austere environments

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Rapid technological innovation in diagnostic imaging requires timely, evidence‐based safety and quality assessment to ensure optimal patient care. This study evaluates a novel multi‐modality extremity imaging system (OXOS MC2) designed for deployment in remote and austere environments.
Xiangyu Yang, Edward J. Stafford, Hadley A. DeBrosse, Yi Wei, Adam Smith, David E. Hintenlang, Nathaniel Bates   +6 more
wiley   +1 more source

Chemical Profiling and In Vitro Assessment of Antioxidant and Antimicrobial Properties of Algerian Erica arborea L. Extracts, Strengthened by Molecular Modeling Analysis

ChemistryOpen, Volume 15, Issue 8, August 2026.
Erica arborea L. from Algeria was valorized via chemical profiling and bioactivity assessment. The EtOAc extract showed the highest levels of polyphenols, flavonoids, and flavonols. It exhibited strong antioxidant (ABTS•+, DPPH•, FRAP) and antibacterial activity (S. aureus, B. subtilis).
Amina Bramki, Ouided Benslama, Fatima Zohra Makhlouf, Anna Andolfi, Zineb Mokhbi, Selsabile Nedjaoum, Chawki Bensouici, Maria Michela Salvatore, Marco Masi   +8 more
wiley   +1 more source

The characterization of a new stabilized lactonase from the endophytic fungi Aspergillus pseudonomiae with anti‐bacterial and anti‐fungal properties

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Microorganisms use diverse small‐molecule signals to coordinate behavior, supporting interspecies and interkingdom communication. These chemical dialogs shape fundamental biological processes and define interactions from cooperation to antagonism.
Dor Ben Tovim, Olena Trofimyuk, Elon Yariv, Gali Prag, Livnat Afriat‐Jurnou   +4 more
wiley   +1 more source

Development of a Disease‐Specific Virtual Malaria Population for Physiologically‐Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Malaria remains a major global health challenge, with an urgent need for new therapies to combat the evolving resistance to anti‐malarial treatments. Physiologically‐based pharmacokinetic (PBPK) modeling offers a promising approach to accurately predict PK, optimize dosing strategies, reduce development time and cost, and de‐risk the ...
Junjie Ding, Qi Pei, Richard M. Hoglund, Joel Tarning   +3 more
wiley   +1 more source

Interface‐Stabilized Glass‐Ceramic/Silver Composite Coatings Enable Predictable Multiband Infrared Stealth Under High‐Temperature Marine Environment

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Infrared (IR) stealth is crucial for improving the survivability of equipment. The growing demand for service in marine environments poses new challenges to the composition and structural design of existing IR stealth coatings. This study first investigates the effects of NaCl/water vapor corrosion on the IR stealth performance of GH3536 and a
Kang Wang, Zehao Chen, Chen Tang, Yu Zhen, Minghui Chen, Fuhui Wang   +5 more
wiley   +1 more source

Hybrid Conjugated Polymer Nanoparticles as a Dual‐Mode Photodynamic–Photothermal Platform for Antibacterial Inactivation

ChemistrySelect, Volume 11, Issue 29, 3 August 2026.
ABSTRACT This study explores a light‐activated antimicrobial strategy by developing hybrid nanoparticles (Cn‐TBT‐NPs) composed of the conjugated polymers Cn‐PPV and PCPDTBT, which combine photodynamic and photothermal effects to inactivate Staphylococcus aureus and Escherichia coli.
Hygor Chaves, Cynthia S. A. Caires, Laís F. Aguilera, Regiane G. Lima, Priscila S. Cavalheri, Montcharles S. Pontes, Samuel L. Oliveira, Anderson R. L. Caires   +7 more
wiley   +1 more source