Results 81 to 90 of about 1,057,321 (155)

Eco‐ductile design of RC columns: Resolving the conflict between embodied carbon and curvature ductility

open access: yesStructural Concrete, EarlyView.
Abstract Reducing embodied carbon emissions in structural design is of critical importance in combating global climate change. However, the increased material usage and heavy confinement reinforcement required to meet high ductility demands in reinforced concrete columns directly conflict with environmental sustainability goals.
Mehmet Kevser Derdiman
wiley   +1 more source

immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions

open access: yesVIEW, EarlyView.
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder   +26 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Integration of Micro‐CT and XRF Mapping for Multimodal 3D Analysis of Polychrome Wooden Artifacts

open access: yesX-Ray Spectrometry, EarlyView.
ABSTRACT Over the past 5 years, computer applications have become crucial to archeological research. Since the 1990s, the focus has transitioned from data management tools to the development of virtual models. Recently, digital documentation of cultural heritage has gained considerable focus, with 3D modeling of objects.
Josiane E. Cavalcante   +10 more
wiley   +1 more source

Credit‐Driven Adaptive Grouping for Refined Cooperative Multi‐Agent Reinforcement Learning

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Policy heterogeneity is crucial for achieving sophisticated coordination in complex collaborative tasks, which has emerged as one of the key challenges in multi‐agent reinforcement learning (MARL) in recent years. Notably, the grouping paradigm has made remarkable progress in addressing policy heterogeneity.
Yirui Liu   +6 more
wiley   +1 more source

Behind the Canvas Curtain: Gender, Visibility, and Spectacle in the 1956 Semenyih Incident in the Malayan Emergency

open access: yesGender &History, EarlyView.
ABSTRACT This article examines the 1956 Semenyih strip–search scandal in British colonial Malaya during the Malayan Emergency, a counterinsurgency campaign shaped by Cold War politics in Southeast Asia, to explore how non‐elite Chinese women navigated surveillance, humiliation, and limited opportunities to have their grievances recognized.
Alison Fong
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown   +2 more
wiley   +1 more source

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

open access: yesCancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal   +16 more
wiley   +1 more source

Independent Filter Company Advertisement, 1899

open access: yes, 1899
This document is an illustrated advertisement for the Theurer Beer Filter. This filter was created and patented by the Independent Filter Company in 1899.
Independent Filter Company;
core  

Blocking protein quality control degradation leads to structural stabilization of DHFR indel variants

open access: yesThe FEBS Journal, EarlyView.
Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet   +6 more
wiley   +1 more source

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