Results 41 to 50 of about 1,313 (212)

Multiscale Modeling of an 8‐Week Combination Regimen of Bemnifosbuvir and Ruzasvir in Patients with Chronic Hepatitis C Virus Infection

Clinical Pharmacology &Therapeutics, EarlyView.
Bemnifosbuvir (BEM) and ruzasvir (RZR) are pan‐genotypic HCV polymerase (NS5B) and NS5A inhibitors, respectively. In a single‐arm study (NCT05904470), 215 treatment‐naïve, adherent participants with chronic HCV (with or without cirrhosis) received BEM 550 mg QD plus RZR 180 mg QD for 8 weeks.
Carolin Zitzmann, Ruy M. Ribeiro, Aurelien Marc, Xiao‐Jian Zhou, Alan S. Perelson   +4 more
wiley   +1 more source

Inclusive Leadership and CEO Gender: The Role of Tenure and Education in an Emerging Economy

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Gender inequality in corporate leadership remains a critical challenge, particularly in emerging economies where institutional constraints shape access to top executive positions. This study examines firm performance differences between women and men CEOs in Ecuador, focusing on the moderating roles of tenure and formal education.
K. N. González‐Soto, R. Samaniego‐Medina, P. Giráldez‐Puig   +2 more
wiley   +1 more source

Research progress and current status of dynamic wave propagation characteristics in rock mass: A review

Deep Underground Science and Engineering, EarlyView.
This review elucidates the velocity–dispersion–attenuation coupling mechanisms of wave propagation in rock masses, compares six representative models, and reveals how pressure, temperature, mineral composition, and anisotropy jointly control dynamic responses in complex geological media.
Jiajun Shu, Tao Li, Ruiqi Yuan, Yue Li, Bingni Wu, Bo Liu, Zhengding Deng, Galindo Rubén, Fausto Molina‐Gómez   +8 more
wiley   +1 more source

Seismic analysis and design of tunnels within fault ground: A review

Deep Underground Science and Engineering, EarlyView.
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang, Yujing Jiang, Xuepeng Zhang, Yuyong Jiao, Ningbo Li, Xiao Wang, Bo Li   +6 more
wiley   +1 more source

Effects of Camber of S‐Series Airfoils on Aerodynamic Performance, Entropy Generation Rate, Irreversibility, and Second Law Efficiency of Horizontal Axis Wind Turbines

Energy Science &Engineering, EarlyView.
Due to the depletion of fossil fuels, enhancing wind turbine efficiency is crucial. Utilizing airfoils with high lift‐to‐drag ratios significantly improves power generation by optimizing aerodynamic parameters. Furthermore, entropy generation analysis serves as an effective method for design optimization by minimizing energy losses and exergy ...
Mitra Yadegari
wiley   +1 more source

Study on Fluid Pressure in Tubing, Dynamic Stress in Reservoir, and Fracture Propagation Morphology During Variable‐Rate Hydraulic Fracturing

Energy Science &Engineering, EarlyView.
Variable‐rate hydraulic fracturing can induce unsteady flow in the tubing, thereby generating fluctuating fluid pressure near the bottom‐hole reservoir. Dynamic stress is generated in the reservoir under the action of fluctuating fluid pressure and propagates as stress waves.
Zhu Ge, Wang Chaojing, Li Weicheng
wiley   +1 more source

The prevalence of Streptococcus equi subsp. equi carriers in the Netherlands

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies equi (S. equi) carriers are thought to be important drivers for strangles outbreaks. Limited data are available on the prevalence of carriers in European horse husbandry settings. Objectives To estimate the prevalence of S.
R. M. A. C. Houben, E. M. Broens, M. J. Broekhuizen‐Stins, M. M. Sloet van Oldruitenborgh‐Oosterbaan, C. van Maanen, J. A. P. Heesterbeek   +5 more
wiley   +1 more source

Changes in Biomarkers of Inflammation and Oxidative Status in Dogs Subjected to Celiotomy or Video-Assisted Ovariohysterectomy

Veterinary Sciences
We evaluated the surgical stress response of dogs undergoing three ovariohysterectomy (OVH) techniques. Twenty-nine healthy females were allocated into groups: celiotomy and ligature (CelioSut), celiotomy and bipolar energy (CelioBip), and a video ...
Fabíola Dalmolin, Camila Peres Rubio, Carla Sordi Furlanetto, Rafael Steffens, Najla Ibrahim Isa Abdel Hadi, Adriellen de Lima da Silva, Paloma Tomazi, Bernardo Nascimento Antunes, Fabiana Elias, Elizabeth Moreira dos Santos Schmidt, Maurício Veloso Brun   +10 more
doaj   +1 more source

Knowledge Management and Innovation in Human Resources: Strategic Competencies for Digital Transformation

Knowledge and Process Management, EarlyView.
ABSTRACT This study examines how knowledge management (KM) structures the dynamics of challenges and competencies associated with digital transformation within the human resources (HR) function in the context of Industry 4.0. Adopting a qualitative, exploratory, and prospective research design, the study combines the Delphi technique with ...
Celso Machado Júnior, Vilma Aparecida Caseiro, Elza Fátima Rosa Veloso, Edson Keyso de Miranda Kubo, Raquel da Silva Pereira, Daielly Melina Nassif Mantovani, Roberto Bazanini, Cristiane Jaciara Furlaneto, Marcia Eleane Braghini Deus Deu   +8 more
wiley   +1 more source

Bem-estar em suínos: manejo no pré-abate: Revisão

Pubvet, 2017
A carne suína é a carne mais consumida no mundo, no Brasil perde apenas para a carne bovina e a carne de frango, e o mercado consumidor dessa carne tem se tornado cada vez mais exigente quanto à qualidade e à origem dos animais consumidos principalmente ...
Islan Barbosa do Carmo, Poliana Leal Oliveira, Yngrid Souza Oliveira, Zoila Catalina Rabanal de Montalván   +3 more
doaj   +1 more source