Results 41 to 50 of about 571,567 (314)
Lemurs Optimizer: A New Metaheuristic Algorithm for Global Optimization
Applied Sciences, 2022 The Lemur Optimizer (LO) is a novel nature-inspired algorithm we propose in this paper. This algorithm’s primary inspirations are based on two pillars of lemur behavior: leap up and dance hub.
Ammar Kamal Abasi +9 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Criteria and Effects of Split Contracts Headquarters in Imamieh and Subject Law of Iran [PDF]
مطالعات فقه و حقوق اسلامیOne of the issues of contract law is the presentation of criteria and effects of the division of contracts according to Imamieh and Iran's subject rights.
Saeideh Bagheri Asl
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Benchmarking of Various LiDAR Sensors for Use in Self-Driving Vehicles in Real-World Environments
Sensors, 2022 In this paper, we report on our benchmark results of the LiDAR sensors Livox Horizon, Robosense M1, Blickfeld Cube, Blickfeld Cube Range, Velodyne Velarray H800, and Innoviz Pro.
Joschua Schulte-Tigges +7 more
doaj +1 more source
, 2020 In the public opinion, livestock production is usually accused of being a major contributor to climate change. On the other hand, the changing climate impacts livestock production in different ways and intensities.
Weeks, Peter, Agethen, Katrin
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A GeoSPARQL Compliance Benchmark
ISPRS International Journal of Geo-Information, 2021 GeoSPARQL is an important standard for the geospatial linked data community, given that it defines a vocabulary for representing geospatial data in RDF, defines an extension to SPARQL for processing geospatial data, and provides support for both ...
Milos Jovanovik +2 more
doaj +1 more source
JiaweiZhuang/pleiades-mpi-benchmark: v0.2.1: updated submission
, 2020 MPI Benchmark on NASA Pleiades ...
Jiawei Zhuang
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source