Results 51 to 60 of about 744,901 (308)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Journal of Nuclear Engineering, 2023 Molten Salt Reactors (MSRs) have recently gained resurged research and development interest in the advanced reactor community. Several computational tools are being developed to capture the strong neutronics/thermal-hydraulics coupling effect in this ...
Mohamed Elhareef +2 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Arhiv za Higijenu Rada i ToksikologijuGlyphosate exposure is commonly assessed using either passive dosimetry or biomonitoring. This study tests the hypothesis that internal dose estimates derived from passive dosimetry are higher and more uncertain than those derived from biomonitoring by ...
Kougias Daniel G. +5 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
The Comprehensive Vertical Ozone Observation Experiment and Result Analysis of Ozone Lidars in China
AtmosphereTo evaluate the detection performance of ozone lidars, the first comprehensive vertical ozone observation experiment in China was conducted at the Xilinhot National Climate Observatory in Inner Mongolia from August to December 2023.
Haiyang Cai +8 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
The Computer Journal, 1976 A simple method of measuring performance is by means of a benchmark program. Unless such a program is carefully constructed it is unlikely to be typical of the many thousands of programs run at an installation. An example benchmark for measuring the processor power of scientific computers is presente d: this is compared with other methods of assessing ...
H. J. Curnow, Brian A. Wichmann
openaire +2 more sources
Normtrooper43/MSSP-Benchmark: MSSP Data Benchmark v1
<p>MSSP data benchmark, including the data generator, benchmark files, and function evalutator.</p ...
Normtrooper43
core +1 more source