Results 151 to 160 of about 2,084 (185)

Population health management through human phenotype ontology with policy for ecosystem improvement. [PDF]

Front Artif Intell
Henry JA.
europepmc   +1 more source

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

Machine learning for N-dimensional spatial reasoning tasks on the web. [PDF]

Front Bioinform
Moody B, Kim J, Kim S, Haehn D.
europepmc   +1 more source

Two stable gut microbiome guilds predict liver tumor class and treatment responses

iMeta, EarlyView.
Gut microbiome alterations are linked to hepatocellular carcinoma (HCC), yet taxon‐based biomarkers often lack reproducibility. Using shotgun metagenomics from 120 resectable HCC (MT) and 76 benign hepatic tumor controls (BT), we reconstructed a stable interaction‐based Two Competing Guilds model (HCC‐TCG) comprising 142 genomes organized into two ...
Yang Liu, Zefan Zhang, Guojun Wu, Bowen Li, Linghua Wang, Jincheng Wang, Zixian Wei, Zhiyue Wang, Jinhua Yang, Kunyu Zhang, Tianqi Zhang, Xin Tao, Tao Chen, Jia Fan, Jian Zhou, Xinrong Yang, Liping Zhao, Yunwei Wei   +17 more
wiley   +1 more source

Ultra-high-scale cytometry-based cellular interaction mapping. [PDF]

Nat Methods
Vonficht D, Jopp-Saile L, Yousefian S, Flore V, Simó Vesperinas I, Teuber R, Avanesyan B, Luo Y, Röthemeier C, Grünschläger F, Fernandez-Vaquero M, Fregona V, Ordoñez-Rueda D, Schmalbrock LK, Deininger L, Yamachui Sitcheu AJ, Gu Z, Funk MC, Mikut R, Heikenwälder M, Eggert A, von Stackelberg A, Kobold S, Krönke J, Keller U, Trumpp A, Hegazy AN, Eckert C, Hübschmann D, Haas S.   +29 more
europepmc   +1 more source

Precision Imaging for Optimized Crohn's Disease Management: Navigating the Evolution of Objective Healing Goals

iRADIOLOGY, EarlyView.
Multimodal imaging enables the transition to transmural healing as a superior therapeutic target in Crohn's disease, facilitating precise stricture characterization and the prediction of long‐term clinical outcomes. Some icons are sourced from Figdraw and have been authorized (ID: ROSUUdd4c2).
Ziman Xiong, Yufan Wang, Shuxin Luo, Zhen Li, Yaqi Shen   +4 more
wiley   +1 more source

Methodological insights into sulfur immobilization techniques on commercial carbon for lithium-sulfur batteries. [PDF]

RSC Adv
Shinkarova Y, Tursynbek M, Kenzhebek M, Tatykayev B, Supiyeva Z, Kerimkul T, Sultanov F, Mentbayeva A.   +7 more
europepmc   +1 more source

PEPbench-Open, Reproducible, and Systematic Benchmarking of Automated Pre-Ejection Period Extraction Algorithms. [PDF]

Psychophysiology
Richer R, Jorkowitz J, Stühler S, Abel L, Kurz M, Oesten M, Griesshammer SG, Albrecht NC, Küderle A, Ostgathe C, Kölpin A, Steigleder T, Rohleder N, Eskofier BM.   +13 more
europepmc   +1 more source

Comparative Evaluation of Open-Source Bioinformatics Pipelines for Full-Length Viral Genome Assembly. [PDF]

Viruses
Zsichla L, Zeeb M, Fazekas D, Áy É, Müller D, Metzner KJ, Kouyos RD, Müller V.   +7 more
europepmc   +1 more source