Results 31 to 40 of about 104,731 (267)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Интеллект. Инновации. Инвестиции, 2019 A strategic approach to the management of investment policy is explored to form a digital economy in the system: society, people, knowledge, nature. The conceptual approach to the formation of public administration subsystems of the strategic priorities ...
N.A. Novitsky
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
DIRECTIONS OF FINANCIAL SECURITY ENFORCEMENT IN THE CENTRAL ASIA COUNTRIES
International Journal of Innovative Technologies in Economy, 2018 Article is devoted to the assessment and analysis of the level of financial security of the economies of the countries of Central Asia, and the definition of the criteria for the development of the financial system, its support and approval in the ...
Nurymova Saule, Yessentay Aigerim
doaj
Ciência Animal Brasileira, 2015 The objective of this research was to estimate reference zootechnical and economic performance indices, evaluate the influence of different types of labor on the technical and economic results and identify the components that had greater ...
Rodrigo de Andrade Ferrazza +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Natural Language Engineering, 2020 AbstractBenchmarks can be a useful step toward the goals of the field (when the benchmark is on the critical path), as demonstrated by the GLUE benchmark, and deep nets such as BERT and ERNIE. The case for other benchmarks such as MUSE and WN18RR is less well established.
openaire +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Oxygen reduction performance measurements: Discrepancies against benchmarks
Battery Energy, 2023 Oxygen electrocatalysis is crucial for renewable energy conversion and storage technologies. Specifically for proton exchange membrane fuel cells (PEMFCs), oxygen reduction reaction (ORR) is the primary reaction that determines performance and costs. The
Shahid Zaman +5 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source