Results 51 to 60 of about 104,731 (267)

Data Foundations for Medical AI: Provenance, Reliability and Limitations of Russian Clinical NLP Resources

Informatics
Russian-language resources for medical natural language processing (NLP) are expanding rapidly; however, their fragmentation, uneven curation, and limited clinical reliability hinder the development of safe machine learning systems for prognosis ...
Arsenii Litvinov, Lev Malishevskii, Evgeny Karpulevich, Iaroslav Bespalov, Yaroslav Nedumov, Sergey Zhdanov, Ivan Oseledets, Evgeniy Shlyakhto, Arutyun Avetisyan   +8 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

A Practical Probabilistic Benchmark for AI Weather Models

Geophysical Research Letters
Since the weather is chaotic, it is necessary to forecast an ensemble of future states. Recently, multiple AI weather models have emerged claiming breakthroughs in deterministic skill. Unfortunately, it is hard to fairly compare ensembles of AI forecasts
Noah D. Brenowitz, Yair Cohen, Jaideep Pathak, Ankur Mahesh, Boris Bonev, Thorsten Kurth, Dale R. Durran, Peter Harrington, Michael S. Pritchard   +8 more
doaj   +1 more source

ProFed: A Benchmark for Proximity-Based Non-IID Federated Learning

Journal of Open Research Software
Federated Learning (FL) has emerged as a key paradigm in machine learning but its performance often deteriorates under non-independent and identically distributed (non-IID) client data.
Davide Domini, Christian Otte Ingemann, Gianluca Aguzzi, Lukas Esterle, Mirko Viroli   +4 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Global Optima for Size Optimization Benchmarks by Branch and Bound Principles

Acta Polytechnica, 2012
This paper searches for global optima for size optimization benchmarks utilizing a method based on branch and bound principles. The goal is to demonstrate the process for finding these global optima on the basis of two examples.
Adéla Pospíšilová, Matej Lepš
doaj  

Bio‐Inspired Optimisation Methods Applied to Low Carbon Power and Energy Problems: A Survey

CAAI Transactions on Intelligence Technology
Bio‐inspired optimisation methods have been widely applied to complex real‐world problems, particularly in low‐carbon power and energy systems, where optimisation tasks often involve high‐dimensional, constrained and mixed‐integer characteristics ...
Tianyu Hu, Shihao Zhao, Yuanjun Guo, Linxin Zhang, Zhile Yang   +4 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

The Use of an Exact Algorithm within a Tabu Search Maximum Clique Algorithm

Algorithms, 2020
Let G=(V,E) be an undirected graph with vertex set V and edge set E. A clique C of G is a subset of the vertices of V with every pair of vertices of C adjacent. A maximum clique is a clique with the maximum number of vertices. A tabu search algorithm for
Derek H. Smith, Roberto Montemanni, Stephanie Perkins   +2 more
doaj   +1 more source