Results 51 to 60 of about 147,603 (316)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Interpretation of geodetic observations of the high-rise buildings displacements
Geodesy and Cartography, 2016 In the article presents a new approach to processing results of geodetic observations of the highrise buildings displacements. As a result of three cycles of observations of the spatial position of deformation marks on the facade of high-rise buildings ...
Roman Schults +3 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Greater Bend community wildfire protection plan [PDF]
, 2006 33 pp. Bookmarks supplied by UO. Referenced maps not included. Published May 16, 2006; captured August 23, 2006.This document outlines the priorities, strategies and action plans for fuels reduction treatments in the greater Bend wildland urban interface.
Lighthall, Kate +2 more
core
Digital HealthObjective A growing number of youth are utilizing digital mental health interventions (DMHIs) for treatment of mental health problems such as anxiety, depression, and ADHD.
Darian Lawrence-Sidebottom +6 more
doaj +1 more source
A novel architecture for achieving high drug loading in amorphous spray dried dispersion tablets
International Journal of Pharmaceutics: X, 2020 Although Amorphous Solid Dispersions (ASDs) effectively increase bioavailability, tablet mass can be high due to the large fraction of excipients needed to stabilize the amorphous drug in the solid state, extend drug supersaturation in solution and ...
Deanna M. Mudie +12 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The Stress-Strain State of the Tribo-Fatigue System Roller-Shaft
Механика машин, механизмов и материалов, 2013 Tribo-fatigue system roller-shaft, working in conditions of contact interaction between the roller and the shaft and the non-contact bending shaft is considered.
S.S. Shcherbakov
doaj
Case Reports in Medicine, 2021 One of the complications of the novel coronavirus disease 2019 (COVID-19) is hypercoagulability. For this reason, patients presenting with COVID-19 are often put on therapeutic or intermediate anticoagulation upon hospitalization.
Anthony V. Thomas +12 more
doaj +1 more source