Results 1 to 10 of about 54,449 (117)
Flavonoid Bioavailability and Attempts for Bioavailability Enhancement [PDF]
Nutrients, 2013 Flavonoids are a group of phytochemicals that have shown numerous health effects and have therefore been studied extensively. Of the six common food flavonoid classes, flavonols are distributed ubiquitously among different plant foods whereas appreciable amounts of isoflavones are found in leguminous plant-based foods.
H P Vasantha Rupasinghe +1 more
exaly +3 more sources
Solubility and Bioavailability Enhancement of Oridonin: A Review. [PDF]
Molecules, 2020 Oridonin (ORI), an ent-kaurene tetracyclic diterpenoid compound, is isolated from Chinese herb Rabdosia rubescens with various biological and pharmacological activities including anti-tumor, anti-microbial and anti-inflammatory effects. However, the clinical application of ORI is limited due to its low solubility and poor bioavailability.
Zhang Y +5 more
europepmc +5 more sources
Thiolated Chitosan Microneedle Patch of Levosulpiride from Fabrication, Characterization to Bioavailability Enhancement Approach [PDF]
Polymers, 2022 Rukhshanda Habib +2 more
exaly +2 more sources
World Journal of Advanced Research and Reviews, 2023 The rate and extent (amount) of unmodified medication absorption from its dose form is referred to as bioavailability. It is one of the critical criteria for achieving optimal medication concentration in the systemic circulation. Bioavailability is a significant factor of a drug's therapeutic efficacy, which is determined by the drug's solubility in ...
Vaishnavi Tejram Gabhane +5 more
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Polymers Enhancing Bioavailability in Drug Delivery
Pharmaceutics, 2022 A drug’s bioavailability, i.e., the extent to and rate at which it enters the systemic circulation, thus accessing the site of action, is largely determined by the properties of the drug [...]
Ana I. Fernandes, Angela F. Jozala
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Natural bio-enhancer for bioavailability enhancement
Current Issues in Pharmacy and Medical Sciences, 2023 Abstract There is a connection between bioavailability and absorption. In the field of pharmacology, this is referred to as a category of absorption and is defined as the proportion of a particular dosage of a drug that does not change and is absorbed into the systemic circulation.
Raj K. Keservani +4 more
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Bioavailability enhancers of herbal origin: An overview [PDF]
Asian Pacific Journal of Tropical Biomedicine, 2013 Recently, the use of herbal medicines has been increased all over the world due to their therapeutic effects and fewer adverse effects as compared to the modern medicines. However, many herbal drugs and herbal extracts despite of their impressive in-vitro findings demonstrates less or negligible in-vivo activity due to their poor lipid solubility or ...
Kritika, Kesarwani +2 more
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Effect of Transferrin on Enhancing Bioavailability of Iron [PDF]
Bioscience, Biotechnology, and Biochemistry, 2004 Transferrin was isolated and purified from bovine plasma. An intestinal segment in situ experiment showed that 19.2% of injected iron was absorbed when FeCl(3) (80 microg Fe/ml) was injected into a duodenum segment of iron-deficient rats. With addition of 10 and 20 mg of purified transferrin/ml, however, ratios of absorbed iron through duodenum ...
CHOI, Inwook +3 more
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Enhancing the bioavailability of resveratrol by combining it with piperine [PDF]
Molecular Nutrition & Food Research, 2011 AbstractScope:Resveratrol (3,5,4′‐trihydroxystilbene) is a phytoalexin shown to possess a multitude of health‐promoting properties in pre‐clinical studies. However, the poor in vivo bioavailability of resveratrol due to its rapid metabolism is being considered as a major obstacle in translating its effects in humans.
Jeremy J, Johnson +6 more
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Buccal films of prednisolone with enhanced bioavailability [PDF]
Drug Delivery, 2014 The conventional formulation of prednisolone is considered to be low in efficacy, primarily on account of their failure in providing and maintaining effective therapeutic drug levels. This study aims to focus on development of a mucoadhesive buccal delivery system with a twofold objective of offering a rapid as well as a prolonged delivery of ...
Rachna, Kumria +3 more
openaire +2 more sources